What is the recommended dosage for Hoodia?

General: No established effective dose; Marketed: 400-1,000 mg/day (no clinical basis)

What are the side effects of Hoodia?

Potential side effects include: Elevated liver enzymes, Elevated blood pressure, Elevated heart rate, Nausea, Skin reactions.

What is hoodia and how may it relate to weight management?

Hoodia gordonii is a succulent plant from southern Africa traditionally used by San Bushmen to suppress hunger during long hunts. Despite early interest, clinical trials have not demonstrated significant appetite-suppressing or weight loss effects. The active compound P57 has poor oral bioavailability.

What dosage of hoodia has been studied in clinical trials?

The limited clinical research available used purified hoodia gordonii extract at doses ranging from 1,110 to 3,330 mg per day. A key Phase II clinical trial was discontinued due to concerns about liver function changes and lack of efficacy. No standardized dosing has been established.

What are the potential side effects of hoodia?

Reported side effects include nausea, vomiting, elevated blood pressure, elevated heart rate, and skin reactions. Liver function abnormalities were observed in clinical trials. Product authenticity is a significant concern, as many commercial hoodia products have been found to contain little or no actual hoodia.

Hoodia
Hoodia

herbal

Aussi connu sous le nom de: Hoodia gordonii, Bushman's Hat, Xhoba

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About

A succulent plant from the Kalahari Desert traditionally used by San people as an appetite suppressant. The only published RCT found no significant appetite reduction vs. placebo, and Unilever discontinued development due to lack of efficacy and safety concerns. Not recommended — included for consumer education.

How It Works

Contains the steroidal glycoside P57 (oxypregnane), which is theorized to act on the hypothalamus to mimic glucose sensing, signaling caloric sufficiency and suppressing appetite. The proposed mechanism involves increasing ATP content in hypothalamic neurons. However, bioavailability of P57 in humans is extremely poor, and the in vivo mechanism remains unverified.

Evidence For Conditions

Pathologie	Note	Études	Participants
Appetite Control	D	1	49	Voir →

Side Effects

Elevated liver enzymes
Elevated blood pressure
Elevated heart rate
Nausea
Skin reactions

Drug & Supplement Interactions

Diabetes medications (theoretical)
Hepatotoxic medications (additive liver risk)

Informez toujours votre professionnel de santé de tous les compléments alimentaires que vous prenez.Informez toujours votre professionnel de santé de tous les compléments que vous prenez.

Related Ingredients

Garcinia Cambogia Green Coffee Bean Extract Bitter Orange Extract Raspberry Ketones

En bref

Posologie: General: No established effective dose; Marketed: 400-1,000 mg/day (no clinical basis)
Formes: capsule powder liquid
Sources naturelles: Hoodia gordonii cactus (Kalahari Desert succulent; CITES-protected endangered species)
Limite supérieure: Safety data insufficient; liver enzyme elevations observed in clinical trial
Meilleur moment: Before meals (as marketed; no clinical basis)

Synthèse des preuves

Appetite Control D

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.