What is the recommended dosage for Caffeine?

General: 100-200 mg/day; Thermogenic: 200-400 mg/day; Pre Exercise: 3-6 mg/kg body weight

What are the side effects of Caffeine?

Potential side effects include: Insomnia, Anxiety and jitteriness, Increased heart rate, Digestive upset, Tolerance development over 1-2 weeks.

What is caffeine and how may it support weight management?

Caffeine is a natural stimulant found in coffee, tea, and various plants. Research indicates it may temporarily increase metabolic rate and enhance fat oxidation during exercise. These effects tend to diminish with regular use due to tolerance development.

What dosage of caffeine has been studied for weight management?

Clinical studies have used caffeine doses ranging from 100 to 400 mg per day for weight management outcomes. The European Food Safety Authority considers up to 400 mg daily as safe for most adults. Individual tolerance varies considerably based on habitual intake.

What are the potential side effects of caffeine supplements?

Side effects may include insomnia, anxiety, increased heart rate, digestive upset, and elevated blood pressure. Caffeine can interact with certain medications including blood thinners and some antidepressants. Doses above 600 mg per day are more likely to cause adverse effects.

Caffeine

thermogenic

Also known as: 1,3,7-Trimethylxanthine, Caffeine Anhydrous, Guarana (caffeine source)

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About

A naturally occurring xanthine alkaloid and the world's most widely consumed psychoactive substance. Caffeine supports metabolic rate and fat oxidation through sympathetic nervous system activation. Extensively studied in clinical trials for its role in energy expenditure and exercise performance.

How It Works

Adenosine receptor antagonist that stimulates the sympathetic nervous system, increasing catecholamine release (epinephrine, norepinephrine). This activates hormone-sensitive lipase, mobilizing fatty acids from adipose tissue, and increases resting metabolic rate by 3-11%.

Evidence For Conditions

Condition	Grade	Studies	Participants
Exercise Performance for Weight Loss	A	40	5000	View →
Fat Oxidation Enhancement	A	13	606	View →
Weight Loss Plateau	C	8	400	View →

Side Effects

Insomnia
Anxiety and jitteriness
Increased heart rate
Digestive upset
Tolerance development over 1-2 weeks

Drug & Supplement Interactions

Adenosine receptor agonists
Lithium (reduced clearance)
Theophylline
MAOIs
Other stimulants (additive effects)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Capsaicin Forskolin Green Tea Extract (EGCG) Synephrine

Quick Facts

Dosage: General: 100-200 mg/day; Thermogenic: 200-400 mg/day; Pre_Exercise: 3-6 mg/kg body weight
Forms: capsule tablet powder liquid
Natural Sources: Coffee beans, Tea leaves, Guarana, Yerba mate, Kola nut, Cacao
Upper Limit: 400 mg/day (FDA general guideline for healthy adults)
Best Time: Morning or pre-exercise; avoid within 6 hours of bedtime; tolerance develops over 1-2 weeks

Evidence Summary

Exercise Performance for Weight Loss A

Fat Oxidation Enhancement A

Weight Loss Plateau C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.