What is the recommended dosage for DHEA?

General: 25-50 mg/day DHEA; Guidance: Guided by serum DHEA-S levels; 7 Keto Dhea: 100 mg 2x/day

What are the side effects of DHEA?

Potential side effects include: Acne, Hair loss, Facial hair growth (women), Mood changes, Hormonal side effects.

What is DHEA and how may it support weight management?

DHEA (dehydroepiandrosterone) is a hormone produced by the adrenal glands that serves as a precursor to sex hormones. DHEA levels decline with age, and some research has explored whether supplementation may influence body composition. Results from clinical trials have been mixed.

What dosage of DHEA has been studied for weight management?

Clinical trials have used 25–100 mg of DHEA per day, with 50 mg being the most common dose for body composition studies. Research has primarily focused on older adults with declining DHEA levels. Study durations ranged from 3 to 12 months.

What are the potential side effects of DHEA supplements?

DHEA is a hormone and may cause androgenic side effects including acne, hair loss, and facial hair growth in women. It may affect hormone-sensitive conditions and interact with hormone therapies. DHEA is banned by many sports organizations. A healthcare provider should be consulted before use.

DHEA

hormonal

Also known as: Dehydroepiandrosterone, DHEA-S, Prasterone, 7-Keto DHEA

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About

A precursor steroid hormone that declines significantly with age. Preliminary clinical trials suggest 7-Keto DHEA, a metabolite that does not convert to sex hormones, may support thermogenesis and healthy body composition when combined with exercise.

How It Works

Precursor steroid hormone that converts to testosterone and estrogen. DHEA levels decline 80% from peak (age 25) by age 75. Supplementation may counteract age-related increases in abdominal fat by improving insulin sensitivity, supporting lean mass, and modulating cortisol's fat-storing effects. 7-Keto DHEA (a metabolite) enhances thermogenesis without converting to sex hormones.

Evidence For Conditions

Condition	Grade	Studies	Participants
Abdominal Fat Reduction	C	5	200	View →

Side Effects

Acne
Hair loss
Facial hair growth (women)
Mood changes
Hormonal side effects

Drug & Supplement Interactions

Hormone-sensitive cancers (avoid)
Antiestrogens (may counteract)
Insulin and diabetes medications
WADA-banned in competitive sports

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Ashwagandha Maca Vitamin D

Quick Facts

Dosage: General: 25-50 mg/day DHEA; Guidance: Guided by serum DHEA-S levels; 7_Keto_Dhea: 100 mg 2x/day
Forms: capsule tablet cream
Natural Sources: Wild yam (marketed as DHEA precursor but body cannot convert diosgenin to DHEA); endogenously produced by adrenal glands
Upper Limit: 50 mg/day for general use; higher doses under medical supervision only
Best Time: Morning (mimics natural diurnal pattern)

Evidence Summary

Abdominal Fat Reduction C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.