What is the recommended dosage for Forskolin?

General: 250 mg standardized to 10% forskolin 2x/day; Weight Management: 50 mg forskolin/day

What are the side effects of Forskolin?

Potential side effects include: Low blood pressure, Increased heart rate, Headache, GI discomfort.

What is forskolin and how may it support weight management?

Forskolin is derived from the root of Coleus forskohlii, a tropical plant. It activates the enzyme adenylyl cyclase, which increases cyclic AMP levels. A small number of clinical trials suggest it may influence body composition, but evidence remains limited.

What dosage of forskolin has been studied in clinical trials?

Clinical studies have used Coleus forskohlii extract standardized to 10% forskolin at doses of 250 mg twice daily, providing 25 mg of forskolin per dose. Study durations have typically been 12 weeks. The overall body of evidence is small.

What are the potential side effects of forskolin?

Forskolin may lower blood pressure and increase heart rate. It may interact with blood pressure medications, blood thinners, and antiplatelet drugs. Gastrointestinal discomfort has been reported in some study participants. Pregnant or breastfeeding women should avoid forskolin.

Forskolin

thermogenic

Also known as: Coleus forskohlii, Coleonol, Colforsin

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About

A diterpene compound from the root of Coleus forskohlii that directly activates adenylyl cyclase, increasing intracellular cAMP levels. Preliminary clinical trials suggest forskolin may support favorable changes in body composition, particularly in overweight men.

How It Works

Directly activates adenylyl cyclase, increasing intracellular cyclic AMP (cAMP) levels. Elevated cAMP activates protein kinase A and hormone-sensitive lipase, promoting lipolysis. Also stimulates thyroid hormone production and testosterone synthesis, which may support metabolic rate.

Evidence For Conditions

Condition	Grade	Studies	Participants
Obesity	C	3	80	View →

Side Effects

Low blood pressure
Increased heart rate
Headache
GI discomfort

Drug & Supplement Interactions

Antihypertensives (additive blood pressure lowering)
Blood thinners (theoretical)
Nitrates

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Caffeine Capsaicin Green Tea Extract (EGCG) Synephrine

Quick Facts

Dosage: General: 250 mg standardized to 10% forskolin 2x/day; Weight_Management: 50 mg forskolin/day
Forms: capsule extract
Natural Sources: Coleus forskohlii root (Indian plant, supplement form only)
Upper Limit: No established UL; may lower blood pressure
Best Time: With meals

Evidence Summary

Obesity C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.