What is the recommended dosage for Garcinia Cambogia?

General: 500-1,500 mg HCA/day (standardized to 50-60% HCA); Weight Management: 1,500-2,800 mg HCA/day in divided doses

What are the side effects of Garcinia Cambogia?

Potential side effects include: Headache, GI discomfort, Liver toxicity (reported in multi-ingredient products), Nausea.

What is garcinia cambogia and how may it support weight management?

Garcinia cambogia is a tropical fruit containing hydroxycitric acid (HCA), which may inhibit the enzyme citrate lyase involved in fat synthesis. Despite widespread marketing, systematic reviews of clinical trials have found mixed and generally modest results for weight loss.

What dosage of garcinia cambogia has been studied in clinical trials?

Clinical trials have used 1,500–3,000 mg per day of garcinia cambogia extract standardized to 50–60% HCA, typically divided into three doses taken 30–60 minutes before meals. Study durations ranged from 8 to 12 weeks.

What are the potential side effects of garcinia cambogia?

Common side effects include headache, digestive discomfort, and nausea. There have been case reports of liver toxicity, though these often involved multi-ingredient products. The FDA has issued warnings about certain garcinia-containing products. Individuals with liver disease should avoid this supplement.

Garcinia Cambogia

herbal

Also known as: Hydroxycitric Acid (HCA), Garcinia gummi-gutta, Malabar Tamarind, Brindleberry

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About

A tropical fruit extract containing hydroxycitric acid (HCA) that has been widely marketed for weight loss. However, Cochrane reviews and the landmark JAMA trial found evidence to be equivocal at best, and hepatotoxicity concerns have been reported in multi-ingredient products.

How It Works

Hydroxycitric acid (HCA) inhibits ATP-citrate lyase, the enzyme that converts citrate to acetyl-CoA for de novo fatty acid synthesis. Also increases hepatic glycogen synthesis, which may suppress appetite via glucoreceptor signaling in the brain. Serotonergic effects may further reduce appetite and emotional eating.

Evidence For Conditions

Condition	Grade	Studies	Participants
Obesity	C	12	800	View →

Side Effects

Headache
GI discomfort
Liver toxicity (reported in multi-ingredient products)
Nausea

Drug & Supplement Interactions

Diabetes medications (may affect blood sugar)
Statins (potential liver concern)
SSRIs (theoretical serotonergic interaction)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Bitter Orange Extract Green Coffee Bean Extract Hoodia Raspberry Ketones

Quick Facts

Dosage: General: 500-1,500 mg HCA/day (standardized to 50-60% HCA); Weight_Management: 1,500-2,800 mg HCA/day in divided doses
Forms: capsule tablet extract
Natural Sources: Garcinia cambogia fruit rind (Southeast Asian tropical fruit)
Upper Limit: 2,800 mg HCA/day; hepatotoxicity cases reported (often in multi-ingredient products)
Best Time: 30-60 minutes before meals

Evidence Summary

Obesity C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.