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Vitamin B12
Vitamin B12

vitamin_mineral

다른 이름: Cobalamin, Methylcobalamin, Cyanocobalamin, Hydroxocobalamin, Adenosylcobalamin

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About





            

                
An essential cofactor for fatty acid metabolism and red blood cell formation. B12 deficiency — which is common in metformin users (10-30%) and vegans — impairs mitochondrial fatty acid oxidation and causes fatigue that limits physical activity. Benefits for weight management are primarily seen when correcting deficiency.

            

        

        

        
        
        

            

  
How It Works





            

                
Essential cofactor for methionine synthase (homocysteine remethylation) and methylmalonyl-CoA mutase (fatty acid and amino acid metabolism). B12 deficiency impairs mitochondrial fatty acid oxidation, leading to abnormal lipid accumulation. Also required for proper red blood cell formation — deficiency causes megaloblastic anemia with profound fatigue, reducing physical activity. Metformin depletes B12 in 10-30% of users.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                건강 상태
                                등급
                                연구
                                참여자
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Post-Bariatric Nutritional Support
                                    
                                
                                
                                    B

                                
                                
                                    10
                                
                                
                                    1000
                                
                                
                                    
                                        보기 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Slow Metabolism
                                    
                                
                                
                                    C

                                
                                
                                    5
                                
                                
                                    9000
                                
                                
                                    
                                        보기 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Acne (rare, at high doses)
                
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                    Diarrhea (rare)
                
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                    Generally very well tolerated
                
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Drug & Supplement Interactions





            
    
                
                
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                    Metformin (depletes B12 — monitor levels)
                
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                    Proton pump inhibitors (reduced absorption)
                
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                    H2 receptor antagonists (reduced absorption)
                
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                    Colchicine (reduced absorption)
                
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                복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    B-Complex
                    
                
                
                
                    Iron
                    
                
                
                
                    Magnesium
                    
                
                
                
                    Zinc
                    
                
                
                
                    Omega-3
                    
                
                
            

        

        
    


    
    












    

        FDA 면책 조항:
        이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.