Iron için Hypothyroid-Related Weight Gain
C Kanıt Küçük çalışmalardan sınırlı kanıt mevcuttur, ancak bazı olumlu sinyaller bulunmaktadır.Iron is required for thyroid peroxidase (TPO), and iron deficiency impairs T4-to-T3 conversion and thyroid hormone synthesis. Meta-analysis of 22 RCTs found correction of iron deficiency improves exercise tolerance and VO2max. Supplement only when deficiency is confirmed.
Sonuç
Iron is required for thyroid peroxidase (TPO), and iron deficiency impairs T4-to-T3 conversion and thyroid hormone synthesis. Meta-analysis of 22 RCTs found correction of iron deficiency improves exercise tolerance and VO2max. Supplement only when deficiency is confirmed.
Key Study Findings
Popülasyon: Hashimoto's thyroiditis patients
Popülasyon: Patients with thyroid diseases
Popülasyon: Patients with alopecia areata (mean age 27.8y)
Key Statistics
22
Çalışmalar
2000
Katılımcılar
Positive
Derece
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Yaygın Kullanılan Dozajlar
- general:
- 8-18 mg/day (RDA)
- menstruatingwomen:
- 18 mg/day
- deficiencycorrection:
- 100-200 mg elemental iron/day under medical guidance
Üst sınır: 45 mg/day (elemental iron); excess iron increases oxidative stress
Araştırmalarda İncelenen Dozajlar
| Dozaj | Süre | Etki | N |
|---|---|---|---|
| None | -- | Neutral | 2851 |
| not applicable | -- | Mixed | 180 |
| Vitamin D | -- | Positive | -- |
| None | -- | Negative | 100 |
| None | -- | Mixed | -- |
| None | -- | Mixed | 218 |
| None | -- | Positive | -- |
| standard replacement doses | -- | Neutral | 3028 |
En iyi alım zamanı: On empty stomach with vitamin C for absorption; avoid with calcium, coffee, tea
Safety & Side Effects
Bildirilen Yan Etkiler
- ⚠ Constipation
- ⚠ Nausea
- ⚠ Stomach pain
- ⚠ Black stools
- ⚠ Oxidative stress (excess iron)
Bilinen Etkileşimler
- ● Levothyroxine (reduced absorption — take 4 hours apart)
- ● Tetracycline antibiotics (reduced absorption)
- ● Calcium supplements (reduced absorption)
- ● Proton pump inhibitors (reduced absorption)
Tolere edilebilir üst alım: 45 mg/day (elemental iron); excess iron increases oxidative stress
Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
Frequently Asked Questions
Does Iron help with Hypothyroid-Related Weight Gain?
How much Iron should I take for Hypothyroid-Related Weight Gain?
Are there side effects of Iron?
How strong is the evidence for Iron and Hypothyroid-Related Weight Gain?
Related Evidence
Iron diğer sağlık durumları için
References
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- [2] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
- [3] Filip Lebiedziński et al.. Nutrients. 2023. Impact of Vitamin D on Immunopathology of Hashimoto's Thyroiditis: From Theory to Practice. doi:10.3390/nu15143174 PubMed
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- [5] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
- [6] Vinesh Dahiya et al.. Endocr Metab Immune Disord Drug Targets. 2022. Role of Dietary Supplements in Thyroid Diseases. doi:10.2174/1871530322666220419125131 PubMed
- [7] Sule Goksin. North Clin Istanb. 2022. Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata. doi:10.14744/nci.2022.78790 PubMed
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- [11] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
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- [14] İrfan Ozer et al.. J Matern Fetal Neonatal Med. 2017. A prospective case control questionnaire study for restless leg syndrome on 600 pregnant women. doi:10.3109/14767058.2016.1170801 PubMed
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