Vitamin D لـ Menopause-Related Weight Gain

C الأدلة أدلة محدودة من دراسات صغيرة، غير أن ثمة بعض الإشارات الإيجابية.

Menopausal women are frequently vitamin D deficient. Supplementation may improve insulin sensitivity and body composition during the menopausal transition. A prospective study (n=4,659) found higher vitamin D associated with less weight gain. Benefits are primarily seen in deficient individuals.

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الخلاصة

Key Study Findings

narrative review

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.

Dose: None مقابل: Placebo التأثير: None None

systematic review n=90

A systematic review on the impact of nutrition and possible supplementation on the deficiency of …

Dose: None مقابل: Placebo التأثير: None None

Randomized Controlled Trial 48 weeks Double-blind

Regular Supplementation With Resveratrol Improves Bone Mineral Density in Postmenopausal Women: A Randomized, Placebo-Controlled Trial.

Dose: 75 mg مقابل: placebo Outcome: None التأثير: None None

المجتمع المدروس: rat

Review

[Lactose intolerance: past and present. Part II].

Dose: 750 mg مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: postmenopausal women

randomized_controlled_trial n=634 12 weeks

Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with …

Dose: ES: magnolia bark extract + isoflavones 60 mg + Lactobacillus sporogenes + calcium + vitamin D3 (1 t مقابل: Placebo التأثير: ES significantly more active on insomnia, irritability, anxiety, depressed mood, asthenia, loss of l not_reported

randomized controlled trial n=89 24 weeks Open-label

Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause.

Dose: 1 tablet/day: soy isoflavones 60mg + lactobacilli 500M spores + calcium 141mg + vitamin D3 5mcg + Ma مقابل: Placebo التأثير: Significantly reduced severity/frequency of all symptoms vs Ca+D; wellbeing good/very good 66.7% vs None

Key Statistics

الدراسات

500

المشاركون

↑

Positive

التقييم

Referenced Papers

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. Review

Journal of drugs … 2025

A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … Systematic Review

Archives of gynecology … 2024 18 اقتباسات

Regular Supplementation With Resveratrol Improves Bone Mineral Density in Postmenopausal Women: A Randomized, Placebo-Controlled Trial. RCT

Journal of bone … 2020 120 اقتباسات

Effects of a phyto complex on well-being of climacteric women. Observational

The journal of … 2015 13 اقتباسات

[Lactose intolerance: past and present. Part II]. Review

Orvosi hetilap 2015 4 اقتباسات

Bone mineral density in patients with alopecia areata treated with long-term intralesional corticosteroids. Other

Journal of drugs … 2013

Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with a natural anxiolytic agent in … RCT

Minerva ginecologica 2011 19 اقتباسات

Multivitamin/mineral supplements and prevention of chronic disease. Review

Evidence report/technology assessment 2006

Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. RCT

Minerva ginecologica 2006

Exercise effects on menopausal risk factors of early postmenopausal women: 3-yr Erlangen fitness osteoporosis prevention study results. Other

Medicine and science … 2005

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:: 600-800 IU/day
weightmanagement:: 2,000-4,000 IU/day (targeting 25(OH)D >30 ng/mL)
deficiencycorrection:: 5,000-10,000 IU/day for 8-12 weeks under medical supervision

الحد الأعلى: 4,000 IU/day (100 mcg); higher doses under medical supervision

الجرعات المدروسة في الأبحاث

الجرعة	المدة	التأثير	ن
None	--	Positive	--
None	--	Negative	90
75 mg	48 weeks	Positive	--
750 mg	--	Positive	--
ES: magnolia bark extract + isoflavones 60 mg + Lactobacillus sporogenes + calcium + vitamin D3 (1 t	12 weeks	Positive	634
1 tablet/day: soy isoflavones 60mg + lactobacilli 500M spores + calcium 141mg + vitamin D3 5mcg + Ma	24 weeks	Positive	89
Multivitamin/mineral supplements	--	Mixed	--

أفضل وقت للتناول: With a meal containing fat for absorption; morning preferred

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

⚠ Hypercalcemia (at very high doses)
⚠ Nausea
⚠ Kidney stones (at excessive doses)

التفاعلات المعروفة

● Statins (may increase statin levels)
● Thiazide diuretics (increased calcium risk)
● Corticosteroids (impair vitamin D metabolism)
● Orlistat (reduced absorption)

الحد الأقصى المسموح به: 4,000 IU/day (100 mcg); higher doses under medical supervision

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Vitamin D help with Menopause-Related Weight Gain?

Based on 6 studies with 500 participants, there is limited but promising evidence that Vitamin D may support Menopause-Related Weight Gain management. Our evidence grade is C (Some Evidence).

How much Vitamin D should I take for Menopause-Related Weight Gain?

Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin D?

Reported side effects may include Hypercalcemia (at very high doses), Nausea, Kidney stones (at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin D and Menopause-Related Weight Gain?

We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

مكونات أخرى لـ Menopause-Related Weight Gain

Maca C

Vitamin D لحالات أخرى

PCOS-Related Weight Management B Obesity B

الخلاصة السريعة

Evidence Strength52%

Moderate confidence

تفصيل الدراسات

RCT (3)Meta (0)Other (3)

قارن البدائل

اعرف كيف تقارن المكونات الأخرى لهذه الحالة.

عرض جميع المكونات لـ Menopause-Related Weight Gain

اعرف المزيد

References

[1] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
[2] Friederike Wylenzek et al.. Arch Gynecol Obstet. 2024. A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … doi:10.1007/s00404-024-07555-6 PubMed
[3] Rachel Hx Wong et al.. J Bone Miner Res. 2020. Regular Supplementation With Resveratrol Improves Bone Mineral Density in Postmenopausal Women: A Randomized, Placebo-Controlled Trial. doi:10.1002/jbmr.4115 PubMed
[4] Tomasella Quattrocchi et al.. J Obstet Gynaecol Res. 2015. Effects of a phyto complex on well-being of climacteric women. doi:10.1111/jog.12659 PubMed
[5] György Miklós Buzás. Orv Hetil. 2015. [Lactose intolerance: past and present. Part II]. doi:10.1556/650.2015.30280 PubMed
[6] Aman Samrao et al.. J Drugs Dermatol. 2013. Bone mineral density in patients with alopecia areata treated with long-term intralesional corticosteroids. PubMed
[7] C Agosta et al.. Minerva Ginecol. 2011. Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with a natural anxiolytic agent in … PubMed
[8] Han-Yo Huang et al.. Evid Rep Technol Assess (Full Rep). 2006. Multivitamin/mineral supplements and prevention of chronic disease. PubMed
[9] M Mucci et al.. Minerva Ginecol. 2006. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. PubMed
[10] Wolfgang Kemmler et al.. Med Sci Sports Exerc. 2005. Exercise effects on menopausal risk factors of early postmenopausal women: 3-yr Erlangen fitness osteoporosis prevention study results. doi:10.1249/01.mss.0000152678.20239.76 PubMed

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