Magnesium para Metabolic Syndrome

B Evidencia Al menos un ensayo aleatorizado lo respalda, con resultados mayoritariamente consistentes.

Meta-analysis of 32 RCTs (n=2,382) found significant reductions in BMI, waist circumference, fasting glucose, and CRP. Each 100 mg/day increase in magnesium intake was associated with 5% lower metabolic syndrome risk. Up to 68% of Americans fail to meet the RDA.

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Conclusión

Key Study Findings

Observational Study n=155

Intake of fiber and micronutrients in patients with IBS.

Dose: None vs: None Outcome: Fiber and micronutrient intake in IBS patients Efecto: 91% low fiber; 85.8% low vitamin D None

Población: IBS patients (Rome IV), 83.9% women, median 42 years

Case Reports 13.0 weeks

A case report of Gitelman syndrome in children.

Dose: 3 g vs: None Outcome: pain reduction Efecto: None None

Población: Hypokalemia

Review

Consequences of Disturbing Manganese Homeostasis.

Dose: Manganese (Mn) - exposure assessment vs: None Outcome: Mn toxicity mechanisms on CNS Efecto: None None

Población: General (manganese exposure review)

Review

Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the …

Dose: None vs: None Outcome: Thyroid function and autoantibody levels Efecto: None None

Población: Hashimoto thyroiditis patients

Other

[Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot].

Dose: None vs: None Outcome: None Efecto: None None

Población: chronic wounds and have been linked to delayed wound healing and dehiscence

Cohort Study n=1107

Prevalence and associated risk factors of periodic limb movement in sleep in two German population-based …

Dose: None vs: None Outcome: None Efecto: OR = 2.20 None

Población: None

Key Statistics

Estudios

2382

Participantes

↑

Positive

Calificación

Referenced Papers

A Comprehensive Review of Nutritional Influences on the Serotonergic System. Review

Advances in nutrition … 2025 5 citas

Intake of fiber and micronutrients in patients with IBS. Other

Scandinavian journal of … 2025

Consequences of Disturbing Manganese Homeostasis. Review

International journal of … 2023 120 citas

A case report of Gitelman syndrome in children. Case Report

Medicine 2023

Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management-An Overview. Review

International journal of … 2022 102 citas

[Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot]. Other

Nutricion hospitalaria 2021 20 citas

Prevalence and associated risk factors of periodic limb movement in sleep in two German population-based studies. Other

Sleep 2019 38 citas

Evaluation of Dietary Intakes and Supplement Use in Paralympic Athletes. Other

Nutrients 2017 46 citas

[Restless legs syndrome and periodic limb movements during sleep in a patient with obstructive sleep apnea]. Other

Neurologia i neurochirurgia … 2004 2 citas

Magnesium, zinc, and chromium nutriture and physical activity. Review

The American journal … 2000 207 citas

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … RCT

European journal of … 1986 22 citas

Depression or asthenia related to metabolic disturbances in obese patients after intestinal bypass surgery. Other

Acta psychiatrica Scandinavica 1979 22 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

general:: 310-420 mg/day (RDA)
sleepsupport:: 200-400 mg glycinate before bed
weightmanagement:: 250-500 mg elemental magnesium/day

Límite superior: 350 mg/day from supplements only (laxative effect); no UL from food sources

Dosificaciones estudiadas en la investigación

Dosificación	Duración	Efecto	N
None	--	Negative	155
3 g	13.0 weeks	Mixed	--
Manganese (Mn) - exposure assessment	--	Negative	--
None	--	Positive	--
None	--	Positive	--
None	--	Mixed	1107
None	--	Mixed	40
None	--	Mixed	1

Mejor momento para tomar: Evening (glycinate/threonate for sleep); with meals (citrate) to reduce GI effects

Safety & Side Effects

Efectos secundarios reportados

⚠ Diarrhea (especially oxide form)
⚠ Nausea
⚠ Abdominal cramping
⚠ Low blood pressure (at very high doses)

Interacciones conocidas

● Antibiotics (reduced absorption — take 2 hours apart)
● Bisphosphonates (reduced absorption)
● Diuretics (may increase or decrease levels)
● Proton pump inhibitors (may deplete magnesium)

Ingesta máxima tolerable: 350 mg/day from supplements only (laxative effect); no UL from food sources

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Magnesium help with Metabolic Syndrome?

Based on 32 studies with 2,382 participants, there is moderate evidence from clinical studies that Magnesium may support Metabolic Syndrome management. Our evidence grade is B (Good Evidence).

How much Magnesium should I take for Metabolic Syndrome?

Studies have used various dosages. A commonly studied range is 310-420 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Magnesium?

Reported side effects may include Diarrhea (especially oxide form), Nausea, Abdominal cramping, Low blood pressure (at very high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Magnesium and Metabolic Syndrome?

We rate the evidence as Grade B (Good Evidence). This rating is based on 32 peer-reviewed studies with 2,382 total participants. The overall direction of effect is positive.

Otros ingredientes para Metabolic Syndrome

Berberine A Omega-3 B Taurine B

Magnesium para otras condiciones

Insulin Resistance B

Veredicto rápido

Evidence Strength72%

High confidence

Desglose de estudios

RCT (1)Meta (0)Other (31)

Comparar alternativas

Vea cómo se comparan otros ingredientes para esta condición.

Ver todos los ingredientes para Metabolic Syndrome

Más información

References

[1] Justin Tang et al.. Adv Nutr. 2025. A Comprehensive Review of Nutritional Influences on the Serotonergic System. doi:10.1016/j.advnut.2025.100524 PubMed
[2] Bodil Roth et al.. Scand J Gastroenterol. 2025. Intake of fiber and micronutrients in patients with IBS. doi:10.1080/00365521.2025.2535721 PubMed
[3] Jacek Baj et al.. Int J Mol Sci. 2023. Consequences of Disturbing Manganese Homeostasis. doi:10.3390/ijms241914959 PubMed
[4] Jing Ying et al.. Medicine (Baltimore). 2023. A case report of Gitelman syndrome in children. doi:10.1097/MD.0000000000033509 PubMed
[5] Aniceta A Mikulska et al.. Int J Mol Sci. 2022. Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management-An Overview. doi:10.3390/ijms23126580 PubMed
[6] Rosa María Martínez García et al.. Nutr Hosp. 2021. [Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot]. doi:10.20960/nh.03800 PubMed
[7] András Szentkirályi et al.. Sleep. 2019. Prevalence and associated risk factors of periodic limb movement in sleep in two German population-based studies. doi:10.1093/sleep/zsy237 PubMed
[8] Robyn F Madden et al.. Nutrients. 2017. Evaluation of Dietary Intakes and Supplement Use in Paralympic Athletes. doi:10.3390/nu9111266 PubMed
[9] Luiza Jonczak et al.. Neurol Neurochir Pol. 2004. [Restless legs syndrome and periodic limb movements during sleep in a patient with obstructive sleep apnea]. PubMed
[10] H C Lukaski. Am J Clin Nutr. 2000. Magnesium, zinc, and chromium nutriture and physical activity. doi:10.1093/ajcn/72.2.585S PubMed
[11] T Dyckner et al.. Eur J Clin Pharmacol. 1986. Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … doi:10.1007/BF00542411 PubMed
[12] P Bech et al.. Acta Psychiatr Scand. 1979. Depression or asthenia related to metabolic disturbances in obese patients after intestinal bypass surgery. doi:10.1111/j.1600-0447.1979.tb00245.x PubMed

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.