What is the recommended dosage for Glutamine?

General: 5-10 g/day; Gut Health: 10-20 g/day; Exercise Recovery: 5-10 g pre/post workout

What are the side effects of Glutamine?

Potential side effects include: Bloating, GI discomfort, Constipation.

What is glutamine and how may it relate to weight management?

Glutamine is the most abundant amino acid in the body, playing roles in immune function and gut health. Some preliminary research suggests it may reduce sugar cravings and support gut barrier function. Direct evidence for glutamine as a weight management supplement is limited.

What dosage of glutamine has been studied in clinical trials?

Clinical studies have used 5–30 grams of glutamine per day. Research related to body composition has typically used 10–20 grams daily for 4–8 weeks. Most glutamine research has focused on gut health, immune function, and exercise recovery rather than weight loss.

What are the potential side effects of glutamine supplements?

Glutamine is generally well tolerated at doses up to 30 grams per day. Some individuals report bloating or abdominal discomfort. Individuals with liver disease, kidney disease, or Reye syndrome should avoid glutamine supplementation. Long-term safety at high doses has not been thoroughly studied.

Glutamine

protein_amino

Also known as: L-Glutamine, Glutamic Acid Amide

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About

The most abundant amino acid in the body, serving as the primary fuel for enterocytes and immune cells. Preliminary clinical trials suggest glutamine supplementation may support gut health, immune function, and healthy body composition in overweight individuals.

How It Works

Most abundant amino acid in the body; primary fuel for enterocytes and immune cells. During caloric restriction and intense exercise, glutamine depletion impairs gut barrier integrity, increasing intestinal permeability and systemic inflammation — both linked to metabolic dysfunction and obesity. Supplementation supports intestinal health, immune function, and may reduce sugar cravings through blood sugar stabilization.

Evidence For Conditions

Condition	Grade	Studies	Participants
Obesity	C	7	300	View →

Side Effects

Bloating
GI discomfort
Constipation

Drug & Supplement Interactions

Lactulose (may reduce effectiveness)
Anticonvulsants (may reduce effectiveness)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

BCAAs Taurine Whey Protein

Quick Facts

Dosage: General: 5-10 g/day; Gut_Health: 10-20 g/day; Exercise_Recovery: 5-10 g pre/post workout
Forms: powder capsule tablet
Natural Sources: Bone broth, Beef, Chicken, Fish, Eggs, Dairy, Cabbage, Spinach
Upper Limit: 40 g/day (well-tolerated in clinical trials)
Best Time: Between meals or pre/post-exercise; may add to protein shakes

Evidence Summary

Obesity C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.