Green Tea Extract (EGCG)
thermogenicAlso known as: Epigallocatechin Gallate, EGCG, Camellia sinensis Extract, GTE
About
A standardized extract from Camellia sinensis rich in epigallocatechin gallate (EGCG), one of the most extensively studied natural compounds for supporting thermogenesis and fat oxidation. Green tea extract has been reviewed in multiple Cochrane and systematic analyses for its role in supporting healthy body weight.
How It Works
Epigallocatechin gallate (EGCG) inhibits catechol-O-methyltransferase (COMT), prolonging norepinephrine signaling and increasing thermogenesis and fat oxidation. Also activates AMPK, which promotes fatty acid oxidation and inhibits lipogenesis in adipocytes.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Obesity | B | 14 | 1500 | View → |
| Abdominal Fat Reduction | B | 8 | 600 | View → |
| Exercise Performance for Weight Loss | C | 6 | 300 | View → |
| Weight Loss Plateau | C | 5 | 300 | View → |
Side Effects
- Nausea on empty stomach
- Insomnia (caffeine content)
- Rare hepatotoxicity at high doses
- Reduced iron absorption
Drug & Supplement Interactions
- Nadolol (reduced bioavailability)
- Iron supplements (reduced absorption)
- Blood thinners (theoretical)
- Other stimulants (additive effects)
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.