What is the recommended dosage for Garcinia Cambogia?

General: 500-1,500 mg HCA/day (standardized to 50-60% HCA); Weight Management: 1,500-2,800 mg HCA/day in divided doses

What are the side effects of Garcinia Cambogia?

Potential side effects include: Headache, GI discomfort, Liver toxicity (reported in multi-ingredient products), Nausea.

What is garcinia cambogia and how may it support weight management?

Garcinia cambogia is a tropical fruit containing hydroxycitric acid (HCA), which may inhibit the enzyme citrate lyase involved in fat synthesis. Despite widespread marketing, systematic reviews of clinical trials have found mixed and generally modest results for weight loss.

What dosage of garcinia cambogia has been studied in clinical trials?

Clinical trials have used 1,500–3,000 mg per day of garcinia cambogia extract standardized to 50–60% HCA, typically divided into three doses taken 30–60 minutes before meals. Study durations ranged from 8 to 12 weeks.

What are the potential side effects of garcinia cambogia?

Common side effects include headache, digestive discomfort, and nausea. There have been case reports of liver toxicity, though these often involved multi-ingredient products. The FDA has issued warnings about certain garcinia-containing products. Individuals with liver disease should avoid this supplement.

Garcinia Cambogia
Garcinia Cambogia

herbal

別名: Hydroxycitric Acid (HCA), Garcinia gummi-gutta, Malabar Tamarind, Brindleberry

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About

A tropical fruit extract containing hydroxycitric acid (HCA) that has been widely marketed for weight loss. However, Cochrane reviews and the landmark JAMA trial found evidence to be equivocal at best, and hepatotoxicity concerns have been reported in multi-ingredient products.

How It Works

Hydroxycitric acid (HCA) inhibits ATP-citrate lyase, the enzyme that converts citrate to acetyl-CoA for de novo fatty acid synthesis. Also increases hepatic glycogen synthesis, which may suppress appetite via glucoreceptor signaling in the brain. Serotonergic effects may further reduce appetite and emotional eating.

Evidence For Conditions

症状・状態	グレード	研究数	参加者数
Obesity	C	12	800	詳細を見る →

Side Effects

Headache
GI discomfort
Liver toxicity (reported in multi-ingredient products)
Nausea

Drug & Supplement Interactions

Diabetes medications (may affect blood sugar)
Statins (potential liver concern)
SSRIs (theoretical serotonergic interaction)

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Related Ingredients

Green Coffee Bean Extract Bitter Orange Extract Hoodia Raspberry Ketones

基本情報

用量: General: 500-1,500 mg HCA/day (standardized to 50-60% HCA); Weight_Management: 1,500-2,800 mg HCA/day in divided doses
剤形: capsule tablet extract
天然の供給源: Garcinia cambogia fruit rind (Southeast Asian tropical fruit)
上限量: 2,800 mg HCA/day; hepatotoxicity cases reported (often in multi-ingredient products)
推奨摂取タイミング: 30-60 minutes before meals

エビデンスの要約

Obesity C

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。