Iron cho Hypothyroid-Related Weight Gain

Q: Does Iron help with Hypothyroid-Related Weight Gain?

Based on 22 studies with 2,000 participants, there is limited but promising evidence that Iron may support Hypothyroid-Related Weight Gain management. Our evidence grade is C (Some Evidence).

Q: How much Iron should I take for Hypothyroid-Related Weight Gain?

Studies have used various dosages. A commonly studied range is 8-18 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Iron?

Reported side effects may include Constipation, Nausea, Stomach pain, Black stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Iron and Hypothyroid-Related Weight Gain?

We rate the evidence as Grade C (Some Evidence). This rating is based on 22 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

C Bằng chứng Bằng chứng hạn chế từ các nghiên cứu nhỏ, nhưng có một số tín hiệu tích cực.

Iron is required for thyroid peroxidase (TPO), and iron deficiency impairs T4-to-T3 conversion and thyroid hormone synthesis. Meta-analysis of 22 RCTs found correction of iron deficiency improves exercise tolerance and VO2max. Supplement only when deficiency is confirmed.

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Kết luận

Key Study Findings

Retrospective cohort n=2851

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.

Dose: None so với: Placebo Hiệu quả: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05

case-control study n=180

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …

Dose: not applicable so với: Placebo Hiệu quả: None None

Review

Impact of Vitamin D on Immunopathology of Hashimoto's Thyroiditis: From Theory to Practice.

Dose: Vitamin D so với: None Outcome: Thyroid autoimmunity modulation Hiệu quả: None None

Đối tượng nghiên cứu: Hashimoto's thyroiditis patients

Case-control n=100

The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women.

Dose: None so với: Placebo Hiệu quả: MD=-7.40 (20.47 vs 27.87 µg/dL) p=0.005

Review

Role of Dietary Supplements in Thyroid Diseases.

Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Patients with thyroid diseases

Observational Study n=218

Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata.

Dose: None so với: AA patients without comorbidity Outcome: Clinical profile and comorbidities Hiệu quả: None p=0.008

Đối tượng nghiên cứu: Patients with alopecia areata (mean age 27.8y)

Key Statistics

Nghiên cứu

2000

Người tham gia

↑

Positive

Xếp hạng

Referenced Papers

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. Other

Journal of cosmetic … 2025 4 trích dẫn

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 trích dẫn

Impact of Vitamin D on Immunopathology of Hashimoto's Thyroiditis: From Theory to Practice. Review

Nutrients 2023 24 trích dẫn

Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management-An Overview. Review

International journal of … 2022 102 trích dẫn

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 trích dẫn

Role of Dietary Supplements in Thyroid Diseases. Review

Endocrine, metabolic & … 2022 8 trích dẫn

Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata. Other

Northern clinics of … 2022 7 trích dẫn

The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women. Other

Cureus 2022 3 trích dẫn

The Potential Prebiotic Berberine Combined With Methimazole Improved the Therapeutic Effect of Graves' Disease Patients Through Regulating the Intestinal Microbiome. Other

Frontiers in immunology 2021 22 trích dẫn

Dietary supplements in hypothyroidism. Other

Acta scientiarum polonorum. … 2021 7 trích dẫn

NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. Observational

Journal of cosmetic … 2019 25 trích dẫn

Methods of treatment patients with androgenetic alopecia based on reference of Department of Dermatology in Cracow. Other

Polski merkuriusz lekarski … 2019 4 trích dẫn

Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis. Review

Thyroid : official … 2017 170 trích dẫn

A prospective case control questionnaire study for restless leg syndrome on 600 pregnant women. Other

The journal of … 2017 8 trích dẫn

Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other

International journal of … 2016 28 trích dẫn

Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. Other

Dermatology research and … 2016 26 trích dẫn

Evaluation and treatment of male and female pattern hair loss. Other

Journal of the … 2005 247 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:: 8-18 mg/day (RDA)
menstruatingwomen:: 18 mg/day
deficiencycorrection:: 100-200 mg elemental iron/day under medical guidance

Giới hạn trên: 45 mg/day (elemental iron); excess iron increases oxidative stress

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
None	--	Neutral	2851
not applicable	--	Mixed	180
Vitamin D	--	Positive	--
None	--	Negative	100
None	--	Mixed	--
None	--	Mixed	218
None	--	Positive	--
standard replacement doses	--	Neutral	3028

Thời điểm dùng tốt nhất: On empty stomach with vitamin C for absorption; avoid with calcium, coffee, tea

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Constipation
⚠ Nausea
⚠ Stomach pain
⚠ Black stools
⚠ Oxidative stress (excess iron)

Tương tác đã biết

● Levothyroxine (reduced absorption — take 4 hours apart)
● Tetracycline antibiotics (reduced absorption)
● Calcium supplements (reduced absorption)
● Proton pump inhibitors (reduced absorption)

Mức hấp thụ tối đa cho phép: 45 mg/day (elemental iron); excess iron increases oxidative stress

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Iron help with Hypothyroid-Related Weight Gain?

Based on 22 studies with 2,000 participants, there is limited but promising evidence that Iron may support Hypothyroid-Related Weight Gain management. Our evidence grade is C (Some Evidence).

How much Iron should I take for Hypothyroid-Related Weight Gain?

Studies have used various dosages. A commonly studied range is 8-18 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Iron?

Reported side effects may include Constipation, Nausea, Stomach pain, Black stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Iron and Hypothyroid-Related Weight Gain?

We rate the evidence as Grade C (Some Evidence). This rating is based on 22 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Iron cho các tình trạng khác

Post-Bariatric Nutritional Support B Exercise Performance for Weight Loss C

Đánh giá nhanh

Evidence Strength52%

Moderate confidence

Phân tích nghiên cứu

RCT (0)Meta (0)Other (22)

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References

[1] Ömer Karakoyun et al.. J Cosmet Dermatol. 2025. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. doi:10.1111/jocd.70037 PubMed
[2] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
[3] Filip Lebiedziński et al.. Nutrients. 2023. Impact of Vitamin D on Immunopathology of Hashimoto's Thyroiditis: From Theory to Practice. doi:10.3390/nu15143174 PubMed
[4] Aniceta A Mikulska et al.. Int J Mol Sci. 2022. Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management-An Overview. doi:10.3390/ijms23126580 PubMed
[5] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
[6] Vinesh Dahiya et al.. Endocr Metab Immune Disord Drug Targets. 2022. Role of Dietary Supplements in Thyroid Diseases. doi:10.2174/1871530322666220419125131 PubMed
[7] Sule Goksin. North Clin Istanb. 2022. Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata. doi:10.14744/nci.2022.78790 PubMed
[8] Muhammad Fawad Aslam et al.. Cureus. 2022. The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women. doi:10.7759/cureus.32123 PubMed
[9] Zhe Han et al.. Front Immunol. 2021. The Potential Prebiotic Berberine Combined With Methimazole Improved the Therapeutic Effect of Graves' Disease Patients Through Regulating the Intestinal Microbiome. doi:10.3389/fimmu.2021.826067 PubMed
[10] Dagmara Woźniak et al.. Acta Sci Pol Technol Aliment. 2021. Dietary supplements in hypothyroidism. doi:10.17306/J.AFS.0985 PubMed
[11] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
[12] Karolina Kozicka et al.. Pol Merkur Lekarski. 2019. Methods of treatment patients with androgenetic alopecia based on reference of Department of Dermatology in Cracow. PubMed
[13] Shiqian Hu et al.. Thyroid. 2017. Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis. doi:10.1089/thy.2016.0635 PubMed
[14] İrfan Ozer et al.. J Matern Fetal Neonatal Med. 2017. A prospective case control questionnaire study for restless leg syndrome on 600 pregnant women. doi:10.3109/14767058.2016.1170801 PubMed
[15] Tee Wei Siah et al.. Int J Trichology. 2016. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. doi:10.4103/0974-7753.188033 PubMed
[16] Kirti Deo et al.. Dermatol Res Pract. 2016. Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. doi:10.1155/2016/6279108 PubMed
[17] Elise A Olsen et al.. J Am Acad Dermatol. 2005. Evaluation and treatment of male and female pattern hair loss. doi:10.1016/j.jaad.2004.04.008 PubMed

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