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Iron cho Hypothyroid-Related Weight Gain

C Bằng chứng Bằng chứng hạn chế từ các nghiên cứu nhỏ, nhưng có một số tín hiệu tích cực.

Iron is required for thyroid peroxidase (TPO), and iron deficiency impairs T4-to-T3 conversion and thyroid hormone synthesis. Meta-analysis of 22 RCTs found correction of iron deficiency improves exercise tolerance and VO2max. Supplement only when deficiency is confirmed.

C

Kết luận

Iron is required for thyroid peroxidase (TPO), and iron deficiency impairs T4-to-T3 conversion and thyroid hormone synthesis. Meta-analysis of 22 RCTs found correction of iron deficiency improves exercise tolerance and VO2max. Supplement only when deficiency is confirmed.

Key Study Findings

case-control study n=180
A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …
Dose: not applicable so với: Placebo
Review
Impact of Vitamin D on Immunopathology of Hashimoto's Thyroiditis: From Theory to Practice.
Dose: Vitamin D Outcome: Thyroid autoimmunity modulation

Đối tượng nghiên cứu: Hashimoto's thyroiditis patients

retrospective cohort study n=3028
Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …
Dose: standard replacement doses so với: Placebo Hiệu quả: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2%
cross_sectional n=232
Dietary supplements in hypothyroidism.
Dose: variable (self-reported supplement use) so với: Placebo Hiệu quả: 85% of participants took dietary supplements; most popular: vitamin D, magnesium, omega-3 age vs lifestyle modification
Randomized Controlled Trial
Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis.
Dose: 100 μg/d so với: Control Outcome: Risk of Hashimoto's thyroiditis

Đối tượng nghiên cứu: Patients with Hashimoto's thyroiditis

Key Statistics

22

Nghiên cứu

2000

Người tham gia

↑

Positive

C

Xếp hạng

Referenced Papers

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. Other
Journal of cosmetic … 2025 4 trích dẫn
A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other
Journal of cosmetic … 2024 7 trích dẫn
Impact of Vitamin D on Immunopathology of Hashimoto's Thyroiditis: From Theory to Practice. Review
Nutrients 2023 24 trích dẫn
Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management-An Overview. Review
International journal of … 2022 102 trích dẫn
Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other
Journal of cosmetic … 2022 22 trích dẫn
Role of Dietary Supplements in Thyroid Diseases. Review
Endocrine, metabolic & … 2022 8 trích dẫn
Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata. Other
Northern clinics of … 2022 7 trích dẫn
The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women. Other
Cureus 2022 3 trích dẫn
The Potential Prebiotic Berberine Combined With Methimazole Improved the Therapeutic Effect of Graves' Disease Patients Through Regulating the Intestinal Microbiome. Other
Frontiers in immunology 2021 22 trích dẫn
Dietary supplements in hypothyroidism. Other
Acta scientiarum polonorum. … 2021 7 trích dẫn
NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. Observational
Journal of cosmetic … 2019 25 trích dẫn
Methods of treatment patients with androgenetic alopecia based on reference of Department of Dermatology in Cracow. Other
Polski merkuriusz lekarski … 2019 4 trích dẫn
Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis. Review
Thyroid : official … 2017 170 trích dẫn
A prospective case control questionnaire study for restless leg syndrome on 600 pregnant women. Other
The journal of … 2017 8 trích dẫn
Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other
International journal of … 2016 28 trích dẫn
Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. Other
Dermatology research and … 2016 26 trích dẫn
Evaluation and treatment of male and female pattern hair loss. Other
Journal of the … 2005 247 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:
8-18 mg/day (RDA)
menstruatingwomen:
18 mg/day
deficiencycorrection:
100-200 mg elemental iron/day under medical guidance

Giới hạn trên: 45 mg/day (elemental iron); excess iron increases oxidative stress

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
not applicable -- Mixed 180
Vitamin D -- Positive --
standard replacement doses -- Neutral 3028
variable (self-reported supplement use) -- Neutral 232
100 μg/d -- Positive --

Thời điểm dùng tốt nhất: On empty stomach with vitamin C for absorption; avoid with calcium, coffee, tea

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • ⚠ Constipation
  • ⚠ Nausea
  • ⚠ Stomach pain
  • ⚠ Black stools
  • ⚠ Oxidative stress (excess iron)

Tương tác đã biết

  • ● Levothyroxine (reduced absorption — take 4 hours apart)
  • ● Tetracycline antibiotics (reduced absorption)
  • ● Calcium supplements (reduced absorption)
  • ● Proton pump inhibitors (reduced absorption)

Mức hấp thụ tối đa cho phép: 45 mg/day (elemental iron); excess iron increases oxidative stress

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Iron help with Hypothyroid-Related Weight Gain?
Based on 22 studies with 2,000 participants, there is limited but promising evidence that Iron may support Hypothyroid-Related Weight Gain management. Our evidence grade is C (Some Evidence).
How much Iron should I take for Hypothyroid-Related Weight Gain?
Studies have used various dosages. A commonly studied range is 8-18 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Iron?
Reported side effects may include Constipation, Nausea, Stomach pain, Black stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Iron and Hypothyroid-Related Weight Gain?
We rate the evidence as Grade C (Some Evidence). This rating is based on 22 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

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