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Ashwagandha لـ Cortisol-Related Weight Gain

B الأدلة تدعم ذلك تجربة عشوائية واحدة على الأقل، مع نتائج متسقة في معظمها.

Systematic review of 12 RCTs found significant cortisol reduction (27.9% in key study). An 8-week RCT (n=52) found reductions in body weight by 3.0% and BMI by 3.0% in chronically stressed adults. Ashwagandha addresses cortisol-driven visceral fat accumulation.

B

الخلاصة

Systematic review of 12 RCTs found significant cortisol reduction (27.9% in key study). An 8-week RCT (n=52) found reductions in body weight by 3.0% and BMI by 3.0% in chronically stressed adults. Ashwagandha addresses cortisol-driven visceral fat accumulation.

Key Study Findings

RCT n=90 12 weeks Double-blind
A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep …
Dose: 125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily مقابل: Placebo < 0.05

Key Statistics

12

الدراسات

700

المشاركون

↑

Positive

B

التقييم

Referenced Papers

A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled … RCT
Advances in therapy 2025
Can Ashwagandha Benefit the Endocrine System?-A Review. Review
International journal of … 2023 43 اقتباسات
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Systematic Review
Phytotherapy research : … 2018 95 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

sleep:
600 mg at bedtime
general:
300-600 mg/day KSM-66 standardized extract
stresscortisol:
600 mg/day

الحد الأعلى: 1,200 mg/day; rare liver injury cases at very high or prolonged doses

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily 12 weeks Positive 90

أفضل وقت للتناول: Morning for energy/cortisol; evening for sleep; with meals

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • ⚠ Drowsiness
  • ⚠ GI discomfort
  • ⚠ Rare liver injury at very high doses
  • ⚠ Thyroid hormone changes

التفاعلات المعروفة

  • ● Thyroid medications (may increase thyroid hormone levels)
  • ● Sedatives (additive drowsiness)
  • ● Immunosuppressants (may stimulate immune system)
  • ● Diabetes medications (may lower blood sugar)

الحد الأقصى المسموح به: 1,200 mg/day; rare liver injury cases at very high or prolonged doses

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Ashwagandha help with Cortisol-Related Weight Gain?
Based on 12 studies with 700 participants, there is moderate evidence from clinical studies that Ashwagandha may support Cortisol-Related Weight Gain management. Our evidence grade is B (Good Evidence).
How much Ashwagandha should I take for Cortisol-Related Weight Gain?
Studies have used various dosages. A commonly studied range is 600 mg at bedtime. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, GI discomfort, Rare liver injury at very high doses, Thyroid hormone changes. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and Cortisol-Related Weight Gain?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 700 total participants. The overall direction of effect is positive.

مكونات أخرى لـ Cortisol-Related Weight Gain

Omega-3 C

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References

  
    
    
    
  1. 
      [1]
      Manasvi Mahadevan et al..
      Adv Ther.
      2025.
      A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled …
      doi:10.1007/s12325-025-03327-z
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Michał Wiciński et al..
      Int J Mol Sci.
      2023.
      Can Ashwagandha Benefit the Endocrine System?-A Review.
      doi:10.3390/ijms242216513
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Karen Savage et al..
      Phytother Res.
      2018.
      GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
      doi:10.1002/ptr.5940
      PubMed
    
    4. 
    
  















    

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