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Vitamin D für Obesity

B Evidenz Mindestens eine randomisierte Studie unterstützt dies, mit überwiegend konsistenten Ergebnissen.

Meta-analysis of 11 RCTs (n=947) found significant BMI reduction in deficient overweight/obese individuals. Mendelian randomization study (n=42,024) confirms causal association between low vitamin D and higher BMI. Correction of deficiency appears critical for benefits.

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Fazit

Meta-analysis of 11 RCTs (n=947) found significant BMI reduction in deficient overweight/obese individuals. Mendelian randomization study (n=42,024) confirms causal association between low vitamin D and higher BMI. Correction of deficiency appears critical for benefits.

Key Study Findings

Randomized Controlled Trial n=240 520 weeks Open-label
Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of …
Dose: None vs.: Laparoscopic Roux-en-Y gastric bypass (LRYGB) Outcome: Nutritional deficiency prevalence at 10 years Wirkung: Iron deficiency: LSG 14% vs LRYGB 41% p=0.017 (iron deficiency)

Population: Severely obese adults undergoing bariatric surgery

Review
Analytical Review on Nutritional Deficiencies in Vegan Diets: Risks, Prevention, and Optimal Strategies.
Dose: None vs.: None Outcome: None Wirkung: None None

Population: None

Review
Sarcopenia in the Aging Process: Pathophysiological Mechanisms, Clinical Implications, and Emerging Therapeutic Approaches.
Dose: None vs.: None Outcome: Sarcopenia progression and muscle function Wirkung: None None

Population: Older adults with sarcopenia (review)

Review
A scoping review: the impact of nutritional status on the efficacy, effectiveness, and immunogenicity of …
Dose: None vs.: None Outcome: None Wirkung: None None

Population: Scoping review: nutritional status and COVID-19 vaccine

systematic review and meta-analysis
Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis.
Dose: None vs.: Placebo Wirkung: None None
genome-wide association study n=312935
Genome wide association study of a Circadian Imbalance Index in 312,935 European ancestry UK Biobank …
Dose: None vs.: Placebo Wirkung: None None

Key Statistics

11

Studien

947

Teilnehmer

Positive

B

Bewertung

Referenced Papers

Advances in nutrition … 2025 5 Zitierungen
Journal of gastroenterology … 2023 16 Zitierungen
Ugeskrift for laeger 2023
International journal of … 2022 107 Zitierungen
Medical sciences (Basel, … 2021 157 Zitierungen
Nutrients 2021 113 Zitierungen
Physiological research 2021 2 Zitierungen
Journal of cachexia, … 2020 365 Zitierungen
Journal of the … 2020 57 Zitierungen
Journal of the … 2019 16 Zitierungen
American journal of … 2018 138 Zitierungen
Indian journal of … 2017 46 Zitierungen
Indian dermatology online … 2016 51 Zitierungen
International journal of … 2016 42 Zitierungen
Clinics in dermatology 2016 19 Zitierungen
Journal of sleep … 2014 236 Zitierungen
Indian journal of … 2013 24 Zitierungen
International journal of … 2011 49 Zitierungen
Current opinion in … 2011 23 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
600-800 IU/day
weightmanagement:
2,000-4,000 IU/day (targeting 25(OH)D >30 ng/mL)
deficiencycorrection:
5,000-10,000 IU/day for 8-12 weeks under medical supervision

Obergrenze: 4,000 IU/day (100 mcg); higher doses under medical supervision

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None 520 weeks Positive 240
None -- Mixed --
None -- Positive --
None -- Mixed --
None -- Mixed --
None -- Mixed 312935
None -- Neutral 138
None -- Positive --

Beste Einnahmezeit: With a meal containing fat for absorption; morning preferred

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Hypercalcemia (at very high doses)
  • Nausea
  • Kidney stones (at excessive doses)

Bekannte Wechselwirkungen

  • Statins (may increase statin levels)
  • Thiazide diuretics (increased calcium risk)
  • Corticosteroids (impair vitamin D metabolism)
  • Orlistat (reduced absorption)

Tolerierbare Höchstaufnahmemenge: 4,000 IU/day (100 mcg); higher doses under medical supervision

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Vitamin D help with Obesity?
Based on 11 studies with 947 participants, there is moderate evidence from clinical studies that Vitamin D may support Obesity management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Obesity?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia (at very high doses), Nausea, Kidney stones (at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Obesity?
We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 947 total participants. The overall direction of effect is positive.

References

  1. [1] Noor A Hakim. J Steroid Biochem Mol Biol. 2026. Coffee consumption and its association with vitamin D level, lifestyle factors, and mental health symptoms among adults in Saudi Arabia. doi:10.1016/j.jsbmb.2025.106923 PubMed
  2. [2] Ilmari Saarinen et al.. Br J Surg. 2025. Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial. doi:10.1093/bjs/znaf132 PubMed
  3. [3] Anshika Malhotra et al.. J Am Nutr Assoc. 2025. Analytical Review on Nutritional Deficiencies in Vegan Diets: Risks, Prevention, and Optimal Strategies. doi:10.1080/27697061.2025.2461218 PubMed
  4. [4] Jet B Muskens et al.. Child Psychiatry Hum Dev. 2025. Novel Insights into Somatic Comorbidities in Children and Adolescents Across Psychiatric Diagnoses: An Explorative Study. doi:10.1007/s10578-023-01587-w PubMed
  5. [5] Justin Tang et al.. Adv Nutr. 2025. A Comprehensive Review of Nutritional Influences on the Serotonergic System. doi:10.1016/j.advnut.2025.100524 PubMed
  6. [6] Larissa Parreira Araújo et al.. Int J Mol Sci. 2025. Sarcopenia in the Aging Process: Pathophysiological Mechanisms, Clinical Implications, and Emerging Therapeutic Approaches. doi:10.3390/ijms262412147 PubMed
  7. [7] Izolde Bouloukaki et al.. Clin Nutr ESPEN. 2025. Vitamin D deficiency and its potential associations on the health status of older patients with chronic obstructive pulmonary disease in … doi:10.1016/j.clnesp.2025.04.013 PubMed
  8. [8] Xinyao Li et al.. Front Neurol. 2025. Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis. doi:10.3389/fneur.2025.1660995 PubMed
  9. [9] Vicka Oktaria et al.. Trop Dis Travel Med Vaccines. 2025. A scoping review: the impact of nutritional status on the efficacy, effectiveness, and immunogenicity of COVID-19 vaccines. doi:10.1186/s40794-025-00258-z PubMed
  10. [10] Sai Zhang et al.. Front Neurol. 2025. A multimodal data-based diagnostic model for predicting vestibular migraine: a retrospective study. doi:10.3389/fneur.2025.1723008 PubMed
  11. [11] Magdalena Żebrowska et al.. Res Sq. 2025. Genome wide association study of a Circadian Imbalance Index in 312,935 European ancestry UK Biobank participants identifies loci related to … doi:10.21203/rs.3.rs-8329341/v1 PubMed
  12. [12] Maria Polyzou et al.. Nutrients. 2025. The Role of Nutrition in the Development, Management, and Prevention of Rheumatoid Arthritis: A Comprehensive Review. doi:10.3390/nu17243826 PubMed
  13. [13] ZhenZhu Zhang et al.. Medicine (Baltimore). 2025. Genetically predicted modifiable risk factors for Helicobacter pylori infection: A Mendelian randomization study. doi:10.1097/MD.0000000000046696 PubMed
  14. [14] Friederike Wylenzek et al.. Arch Gynecol Obstet. 2024. A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … doi:10.1007/s00404-024-07555-6 PubMed
  15. [15] Bodil Roth et al.. BMC Gastroenterol. 2024. Overweight and vitamin D deficiency are common in patients with irritable bowel syndrome - a cross-sectional study. doi:10.1186/s12876-024-03373-x PubMed
  16. [16] Sushil K Jain et al.. Nutrients. 2024. The Impact of Vitamin D and L-Cysteine Co-Supplementation on Upregulating Glutathione and Vitamin D-Metabolizing Genes and in the Treatment of … doi:10.3390/nu16132004 PubMed
  17. [17] Hannah Wilcox et al.. J Eat Disord. 2024. Clinical and genetic associations for night eating syndrome in a patient biobank. doi:10.1186/s40337-024-01180-z PubMed
  18. [18] Fangfang Song et al.. Asia Pac J Clin Nutr. 2024. Vitamin D and CRP are associated in hospitalized inflammatory bowel disease (IBD) patients in Shanghai. doi:10.6133/apjcn.202409_33(3).0007 PubMed
  19. [19] Yun-Yang Hu et al.. Zhongguo Dang Dai Er Ke Za Zhi. 2024. [Advances in Mendelian randomization studies on autism spectrum disorder]. doi:10.7499/j.issn.1008-8830.2311030 PubMed
  20. [20] David C Whitcomb et al.. Gastroenterology. 2023. AGA Clinical Practice Update on the Epidemiology, Evaluation, and Management of Exocrine Pancreatic Insufficiency: Expert Review. doi:10.1053/j.gastro.2023.07.007 PubMed
  21. [21] Hanane Touil et al.. Front Immunol. 2023. Differential impact of environmental factors on systemic and localized autoimmunity. doi:10.3389/fimmu.2023.1147447 PubMed
  22. [22] Wu Yanping et al.. J Gastroenterol Hepatol. 2023. The interaction between obesity and visceral hypersensitivity. doi:10.1111/jgh.16083 PubMed
  23. [23] Charlotte Näslund-Koch et al.. Ugeskr Laeger. 2023. [Not Available]. PubMed
  24. [24] Birgitta Dresp-Langley et al.. Int J Environ Res Public Health. 2022. Digital Addiction and Sleep. doi:10.3390/ijerph19116910 PubMed
  25. [25] Ninghao Huang et al.. Nutrients. 2022. Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants. doi:10.3390/nu14112273 PubMed
  26. [26] Carolyn Ee et al.. Women Birth. 2022. Complementary medicines and therapies in clinical guidelines on pregnancy care: A systematic review. doi:10.1016/j.wombi.2021.08.003 PubMed
  27. [27] Mohammad Yazdchi et al.. Curr J Neurol. 2022. Sleep status in multiple sclerosis: Role of vitamin D and body mass index. doi:10.18502/cjn.v21i2.10489 PubMed
  28. [28] Rosalia Silvestri et al.. Front Psychiatry. 2022. Behavioral sleep medicine-The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental … doi:10.3389/fpsyt.2022.1003019 PubMed
  29. [29] Sule Goksin. North Clin Istanb. 2022. Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata. doi:10.14744/nci.2022.78790 PubMed
  30. [30] Kathy M Redfern et al.. Nutrients. 2022. Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use … doi:10.3390/nu14235135 PubMed
  31. [31] Wan-Jun Yin et al.. Front Nutr. 2022. Sleep patterns modify the association of 25(OH)D with poor cardiovascular health in pregnant women. doi:10.3389/fnut.2022.1013960 PubMed
  32. [32] Sapna P Sadarangani et al.. NPJ Vaccines. 2022. DYNAMIC cohort study evaluating metabolic predictors of influenza vaccine immune response in older adults. doi:10.1038/s41541-022-00548-z PubMed
  33. [33] Izolde Bouloukaki et al.. Fam Pract. 2022. Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters. doi:10.1093/fampra/cmac012 PubMed
  34. [34] A U Larsen et al.. Sleep Med X. 2022. Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study. doi:10.1016/j.sleepx.2022.100056 PubMed
  35. [35] Krishna C Thandra et al.. Med Sci (Basel). 2021. Epidemiology of Non-Hodgkin's Lymphoma. doi:10.3390/medsci9010005 PubMed
  36. [36] Giulia Marrone et al.. Nutrients. 2021. Vegan Diet Health Benefits in Metabolic Syndrome. doi:10.3390/nu13030817 PubMed
  37. [37] Mette M Berger et al.. Clin Nutr ESPEN. 2021. Strengthening the immunity of the Swiss population with micronutrients: A narrative review and call for action. doi:10.1016/j.clnesp.2021.03.012 PubMed
  38. [38] Sushil K Jain et al.. J Am Coll Nutr. 2021. l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 Secretion in High Glucose Treated … doi:10.1080/07315724.2020.1850371 PubMed
  39. [39] Rosa María Martínez García et al.. Nutr Hosp. 2021. [Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot]. doi:10.20960/nh.03800 PubMed
  40. [40] Laura Heusschen et al.. Obes Surg. 2021. Optimizing Multivitamin Supplementation for Sleeve Gastrectomy Patients. doi:10.1007/s11695-021-05282-4 PubMed
  41. [41] A U Larsen et al.. Sleep Med X. 2021. No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial. doi:10.1016/j.sleepx.2021.100040 PubMed
  42. [42] Saeed M Alamoudi et al.. Cureus. 2021. Association Between Vitamin D and Zinc Levels With Alopecia Areata Phenotypes at a Tertiary Care Center. doi:10.7759/cureus.14738 PubMed
  43. [43] L Máčová et al.. Physiol Res. 2021. Endocrine risk factors for COVID-19 in context of aging. doi:10.33549/physiolres.934723 PubMed
  44. [44] Ben Kirk et al.. J Cachexia Sarcopenia Muscle. 2020. Osteosarcopenia: epidemiology, diagnosis, and treatment-facts and numbers. doi:10.1002/jcsm.12567 PubMed
  45. [45] R Z Conic et al.. J Eur Acad Dermatol Venereol. 2020. Comorbidities in pediatric alopecia areata. doi:10.1111/jdv.16727 PubMed
  46. [46] Payam Sharifan et al.. Food Sci Nutr. 2020. Efficacy of low-fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of … doi:10.1002/fsn3.1750 PubMed
  47. [47] Elahe Allahyari et al.. Nutr Health. 2020. The relationship between neuropsychological function and responsiveness to vitamin D supplementation using artificial neural networks. doi:10.1177/0260106020937190 PubMed
  48. [48] Hui-Jun Zhang et al.. Acta Neurol Scand. 2019. Relationship between 25-Hydroxyvitamin D, bone density, and Parkinson's disease symptoms. doi:10.1111/ane.13141 PubMed
  49. [49] Alicia C Jarosz et al.. J Acad Nutr Diet. 2019. Association between Vitamin D Status and Premenstrual Symptoms. doi:10.1016/j.jand.2018.06.014 PubMed
  50. [50] Elio Kechichian et al.. Am J Clin Dermatol. 2018. Vitamin D and the Skin: An Update for Dermatologists. doi:10.1007/s40257-017-0323-8 PubMed
  51. [51] Anabelle Cloutier et al.. Surg Obes Relat Dis. 2018. Long alimentary limb duodenal switch (LADS): a short-term prospective randomized trial. doi:10.1016/j.soard.2017.08.028 PubMed
  52. [52] Robyn F Madden et al.. Nutrients. 2017. Evaluation of Dietary Intakes and Supplement Use in Paralympic Athletes. doi:10.3390/nu9111266 PubMed
  53. [53] Yasmeen Jabeen Bhat et al.. Indian J Dermatol. 2017. Vitamin D Level in Alopecia Areata. doi:10.4103/ijd.IJD_677_16 PubMed
  54. [54] Benjamin Udoka Nwosu et al.. PLoS One. 2017. Vitamin D status in pediatric irritable bowel syndrome. doi:10.1371/journal.pone.0172183 PubMed
  55. [55] S C Gominak. Med Hypotheses. 2016. Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid … doi:10.1016/j.mehy.2016.07.007 PubMed
  56. [56] Ola Ahmed Bakry et al.. Indian Dermatol Online J. 2016. Serum Vitamin D in patients with alopecia areata. doi:10.4103/2229-5178.190504 PubMed
  57. [57] Mahnaz Banihashemi et al.. Int J Trichology. 2016. Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss. doi:10.4103/0974-7753.188965 PubMed
  58. [58] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
  59. [59] Joshua Bauml et al.. Breast Cancer Res. 2015. Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with co-morbid fatigue and insomnia? doi:10.1186/s13058-015-0599-7 PubMed
  60. [60] Michael A Grandner et al.. J Sleep Res. 2014. Sleep symptoms associated with intake of specific dietary nutrients. doi:10.1111/jsr.12084 PubMed
  61. [61] H Himmerich et al.. Nervenarzt. 2014. [Nutrition and dietary supplements in psychiatric diseases]. doi:10.1007/s00115-014-4163-y PubMed
  62. [62] Judy R Rees et al.. Clin Infect Dis. 2013. Vitamin D3 supplementation and upper respiratory tract infections in a randomized, controlled trial. doi:10.1093/cid/cit549 PubMed
  63. [63] M K Taneja et al.. Indian J Otolaryngol Head Neck Surg. 2013. Vitamin d deficiency in e.N.T. Patients. doi:10.1007/s12070-012-0603-9 PubMed
  64. [64] Elisabeth A Frazier et al.. J Child Adolesc Psychopharmacol. 2013. Nutritional and safety outcomes from an open-label micronutrient intervention for pediatric bipolar spectrum disorders. doi:10.1089/cap.2012.0098 PubMed
  65. [65] Aman Samrao et al.. J Drugs Dermatol. 2013. Bone mineral density in patients with alopecia areata treated with long-term intralesional corticosteroids. PubMed
  66. [66] David Reid et al.. Int J Pediatr Otorhinolaryngol. 2011. Vitamin D and tonsil disease--preliminary observations. doi:10.1016/j.ijporl.2010.11.012 PubMed
  67. [67] Mark P Tighe et al.. Curr Opin Clin Nutr Metab Care. 2011. Nutrition and inflammatory bowel disease: primary or adjuvant therapy. doi:10.1097/MCO.0b013e328349eb4d PubMed
  68. [68] C Agosta et al.. Minerva Ginecol. 2011. Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with a natural anxiolytic agent in … PubMed
  69. [69] Adit A Ginde et al.. Arch Intern Med. 2009. Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. doi:10.1001/archinternmed.2008.560 PubMed
  70. [70] E Ron et al.. J Natl Cancer Inst. 1987. A population-based case-control study of thyroid cancer. PubMed
  71. [71] P Bech et al.. Acta Psychiatr Scand. 1979. Depression or asthenia related to metabolic disturbances in obese patients after intestinal bypass surgery. doi:10.1111/j.1600-0447.1979.tb00245.x PubMed

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