Vitamin D для Obesity
B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.Meta-analysis of 11 RCTs (n=947) found significant BMI reduction in deficient overweight/obese individuals. Mendelian randomization study (n=42,024) confirms causal association between low vitamin D and higher BMI. Correction of deficiency appears critical for benefits.
Итог
Meta-analysis of 11 RCTs (n=947) found significant BMI reduction in deficient overweight/obese individuals. Mendelian randomization study (n=42,024) confirms causal association between low vitamin D and higher BMI. Correction of deficiency appears critical for benefits.
Key Study Findings
Популяция: Severely obese adults undergoing bariatric surgery
Популяция: None
Популяция: Older adults with sarcopenia (review)
Популяция: Scoping review: nutritional status and COVID-19 vaccine
Key Statistics
11
Исследования
947
Участники
Positive
Оценка
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 600-800 IU/day
- weightmanagement:
- 2,000-4,000 IU/day (targeting 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 5,000-10,000 IU/day for 8-12 weeks under medical supervision
Верхний предел: 4,000 IU/day (100 mcg); higher doses under medical supervision
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| None | 520 weeks | Positive | 240 |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | 312935 |
| None | -- | Neutral | 138 |
| None | -- | Positive | -- |
Лучшее время приёма: With a meal containing fat for absorption; morning preferred
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ Hypercalcemia (at very high doses)
- ⚠ Nausea
- ⚠ Kidney stones (at excessive doses)
Известные взаимодействия
- ● Statins (may increase statin levels)
- ● Thiazide diuretics (increased calcium risk)
- ● Corticosteroids (impair vitamin D metabolism)
- ● Orlistat (reduced absorption)
Допустимый верхний уровень потребления: 4,000 IU/day (100 mcg); higher doses under medical supervision
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Vitamin D help with Obesity?
How much Vitamin D should I take for Obesity?
Are there side effects of Vitamin D?
How strong is the evidence for Vitamin D and Obesity?
Related Evidence
Другие ингредиенты для Obesity
Vitamin D для других состояний
References
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