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Ashwagandha para Cortisol-Related Weight Gain

B Evidencia Al menos un ensayo aleatorizado lo respalda, con resultados mayoritariamente consistentes.

Systematic review of 12 RCTs found significant cortisol reduction (27.9% in key study). An 8-week RCT (n=52) found reductions in body weight by 3.0% and BMI by 3.0% in chronically stressed adults. Ashwagandha addresses cortisol-driven visceral fat accumulation.

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B

Conclusión

Systematic review of 12 RCTs found significant cortisol reduction (27.9% in key study). An 8-week RCT (n=52) found reductions in body weight by 3.0% and BMI by 3.0% in chronically stressed adults. Ashwagandha addresses cortisol-driven visceral fat accumulation.

Key Study Findings

RCT n=90 12 weeks Double-blind
A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep …
Dose: 125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily vs: Placebo Efecto: None < 0.05
Review
Can Ashwagandha Benefit the Endocrine System?-A Review.
Dose: None vs: Placebo Efecto: None None

Key Statistics

12

Estudios

700

Participantes

Positive

B

Calificación

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

sleep:
600 mg at bedtime
general:
300-600 mg/day KSM-66 standardized extract
stresscortisol:
600 mg/day

Límite superior: 1,200 mg/day; rare liver injury cases at very high or prolonged doses

Dosificaciones estudiadas en la investigación

Dosificación Duración Efecto N
125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily 12 weeks Positive 90
None -- Positive --

Mejor momento para tomar: Morning for energy/cortisol; evening for sleep; with meals

Safety & Side Effects

Efectos secundarios reportados

  • Drowsiness
  • GI discomfort
  • Rare liver injury at very high doses
  • Thyroid hormone changes

Interacciones conocidas

  • Thyroid medications (may increase thyroid hormone levels)
  • Sedatives (additive drowsiness)
  • Immunosuppressants (may stimulate immune system)
  • Diabetes medications (may lower blood sugar)

Ingesta máxima tolerable: 1,200 mg/day; rare liver injury cases at very high or prolonged doses

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Ashwagandha help with Cortisol-Related Weight Gain?
Based on 12 studies with 700 participants, there is moderate evidence from clinical studies that Ashwagandha may support Cortisol-Related Weight Gain management. Our evidence grade is B (Good Evidence).
How much Ashwagandha should I take for Cortisol-Related Weight Gain?
Studies have used various dosages. A commonly studied range is 600 mg at bedtime. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, GI discomfort, Rare liver injury at very high doses, Thyroid hormone changes. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and Cortisol-Related Weight Gain?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 700 total participants. The overall direction of effect is positive.

Otros ingredientes para Cortisol-Related Weight Gain

References

  1. [1] Manasvi Mahadevan et al.. Adv Ther. 2025. A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled … doi:10.1007/s12325-025-03327-z PubMed
  2. [2] Michał Wiciński et al.. Int J Mol Sci. 2023. Can Ashwagandha Benefit the Endocrine System?-A Review. doi:10.3390/ijms242216513 PubMed
  3. [3] Karen Savage et al.. Phytother Res. 2018. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. doi:10.1002/ptr.5940 PubMed

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.