What is the recommended dosage for Omega-3?

General: 250-500 mg EPA+DHA/day; Anti Inflammatory: 2,000-4,000 mg/day; Weight Management: 1,000-3,000 mg EPA+DHA/day

What are the side effects of Omega-3?

Potential side effects include: Fishy aftertaste, GI discomfort, Increased bleeding time (at high doses), Nausea.

What are omega-3 fatty acids and how may they relate to weight management?

Omega-3 fatty acids (EPA and DHA) are essential fats found in fatty fish and fish oil. Some clinical studies suggest omega-3 supplementation may reduce inflammation, improve insulin sensitivity, and modestly support body composition changes when combined with exercise. Effects on body weight alone are generally small.

What dosage of omega-3 has been studied for weight management?

Clinical trials have used 1–4 grams of combined EPA and DHA per day for weight-related outcomes. Most studies lasted 8–24 weeks. The American Heart Association recommends 2 servings of fatty fish per week for general health, equivalent to approximately 500 mg of EPA+DHA per day.

What are the potential side effects of omega-3 supplements?

Common side effects include fishy aftertaste, burping, and digestive discomfort. High doses (above 3 grams daily) may increase bleeding risk and should be used cautiously with anticoagulant medications. Omega-3 supplements may contain contaminants such as mercury; choosing purified, third-party tested products is recommended.

Omega-3
Omega-3

vitamin_mineral

別名: EPA, DHA, Fish Oil, Eicosapentaenoic Acid, Docosahexaenoic Acid, Algal DHA

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About

Essential fatty acids (EPA and DHA) that modulate adipose tissue inflammation and metabolic function. Systematic reviews of 44 RCTs demonstrate omega-3 supplementation may support healthy triglyceride levels and waist circumference, especially when combined with exercise.

How It Works

EPA and DHA modulate adipose tissue inflammation by replacing arachidonic acid in cell membranes, shifting eicosanoid production from pro-inflammatory (PGE2, LTB4) to anti-inflammatory mediators (resolvins, protectins). Activate PPAR-gamma in adipose tissue, improving insulin sensitivity. Enhance fat oxidation through AMPK activation and reduce lipogenesis via SREBP-1c suppression.

Evidence For Conditions

症状・状態	グレード	研究数	参加者数
Metabolic Syndrome	B	44	3000	詳細を見る →
Abdominal Fat Reduction	B	21	1329	詳細を見る →
Cortisol-Related Weight Gain	C	5	300	詳細を見る →

Side Effects

Fishy aftertaste
GI discomfort
Increased bleeding time (at high doses)
Nausea

Drug & Supplement Interactions

Blood thinners (may enhance anticoagulant effect at high doses)
Blood pressure medications (additive effect)
Orlistat (reduced absorption)

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Related Ingredients

B-Complex Iron Magnesium Zinc Vitamin B12

基本情報

用量: General: 250-500 mg EPA+DHA/day; Anti_Inflammatory: 2,000-4,000 mg/day; Weight_Management: 1,000-3,000 mg EPA+DHA/day
剤形: softgel liquid capsule gummy
天然の供給源: Fatty fish (salmon, mackerel, sardines), Walnuts, Flaxseeds, Chia seeds, Algae
上限量: 5,000 mg EPA+DHA/day (FDA GRAS); may increase bleeding time at high doses
推奨摂取タイミング: With meals containing fat for absorption; may split dose AM/PM

エビデンスの要約

Metabolic Syndrome B

Abdominal Fat Reduction B

Cortisol-Related Weight Gain C

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