[Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot].

Rosa María Martínez García, Rosa María Fuentes Chacón, Ana María Lorenzo Mora, Rosa M Ortega Anta

Other Nutricion hospitalaria 2021 20 citations

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Study Design

Study Type: Other
Population: chronic wounds and have been linked to delayed wound healing and dehiscence

Intervention: [Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot]. None
Comparator: None
Primary Outcome: None
Effect Direction: Positive
Risk of Bias: Unclear

Abstract

Nutrition plays an essential role in chronic wound healing as extra nutrients are needed for tissue repair and to restore losses through wound exudate. Insufficient intake of energy, protein, antioxidants (vitamin C, A, and zinc) and vitamin D are common in patients with chronic wounds and have been linked to delayed wound healing and dehiscence. Other risk factors such as obesity, diabetes, advanced age, corticosteroid use, and dehydration can also reduce or impede the healing process, and nutritional screening is important to identify patients with malnutrition. Proteins, amino acids (arginine, glutamine and methionine), vitamins C and A, and zinc have been used as pharmacological nutrients in pressure ulcer healing; however, omega-3 fatty acids, although they appear to slow progression, do not show improved healing rates. In patients with diabetic foot, supplementation with vitamins D, C, A, and E, magnesium, zinc, omega-3 fatty acids, and probiotics reduces ulcer size and improves glycemic control, although they have not been associated with complete healing; however, supplementation with arginine, glutamine, and β-hydroxy-β-methylbutyrate does show wound healing, although further evidence is needed to confirm these results.

TL;DR

In patients with diabetic foot, supplementation with vitamins D, C, A, and E, magnesium, zinc, omega-3 fatty acids, and probiotics reduces ulcer size and improves glycemic control, although they have not been associated with complete healing.