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Bitter Orange Extract
Bitter Orange Extract

herbal

别名: Citrus aurantium, Synephrine Source, Zhi Shi (TCM), Seville Orange

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About





            

                
A botanical extract from Citrus aurantium peel containing p-synephrine and flavonoids. Safety reviews of clinical studies have not identified significant adverse cardiovascular effects at standard doses, but FDA adverse event reports associated with multi-ingredient products limit conclusions about isolated efficacy.

            

        

        

        
        
        

            

  
How It Works





            

                
Contains p-synephrine (primary active), octopamine, and naringin. P-synephrine selectively activates beta-3 adrenergic receptors in adipose tissue, stimulating lipolysis and thermogenesis. Naringin and hesperidin (flavonoids) provide synergistic metabolic effects through AMPK activation and improved insulin sensitivity.

            

        

        

        
        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Increased heart rate (in combination products)
                
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                    Headache
                
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                    GI discomfort
                
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Drug & Supplement Interactions





            
    
                
                
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                    MAOIs
                
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                    Caffeine and other stimulants (avoid combination)
                
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                    CYP3A4 substrates (naringin inhibits CYP3A4)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Garcinia Cambogia
                    
                
                
                
                    Green Coffee Bean Extract
                    
                
                
                
                    Hoodia
                    
                
                
                
                    Raspberry Ketones
                    
                
                
            

        

        
    


    
    










    

        FDA 免责声明:
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