HoodiaHoodia
herbal
别名: Hoodia gordonii, Bushman's Hat, Xhoba
About
A succulent plant from the Kalahari Desert traditionally used by San people as an appetite suppressant. The only published RCT found no significant appetite reduction vs. placebo, and Unilever discontinued development due to lack of efficacy and safety concerns. Not recommended — included for consumer education.
How It Works
Contains the steroidal glycoside P57 (oxypregnane), which is theorized to act on the hypothalamus to mimic glucose sensing, signaling caloric sufficiency and suppressing appetite. The proposed mechanism involves increasing ATP content in hypothalamic neurons. However, bioavailability of P57 in humans is extremely poor, and the in vivo mechanism remains unverified.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| Appetite Control | D | 1 | 49 | 查看 → |
Side Effects
- Elevated liver enzymes
- Elevated blood pressure
- Elevated heart rate
- Nausea
- Skin reactions
Drug & Supplement Interactions
- Diabetes medications (theoretical)
- Hepatotoxic medications (additive liver risk)
请务必告知您的医疗保健提供者您正在服用的所有补充剂。
Related Ingredients
FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。