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Synephrine ： Fat Oxidation Enhancement

B

Systematic review of 20 studies found p-synephrine at 25-100 mg/day increases resting metabolic rate by 65-183 kcal/day. It is a selective beta-3 agonist without significant cardiovascular stimulation. A 12-week RCT (n=70) found greater weight loss with synephrine plus hesperidin versus placebo.

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            B

        

        

            
結論

            
            
Systematic review of 20 studies found p-synephrine at 25-100 mg/day increases resting metabolic rate by 65-183 kcal/day. It is a selective beta-3 agonist without significant cardiovascular stimulation. A 12-week RCT (n=70) found greater weight loss with synephrine plus hesperidin versus placebo.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
20

        
研究数

    

    

        
1000

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
10-20 mg p-synephrine 1-3x/day

                    

                    
                    

                        
preexercise:

                        
50 mg 45 min before

                    

                    
                    

                        
weightmanagement:

                        
25-50 mg/day

                    

                    
                

                
                

                    上限量： 100 mg/day; avoid combination with other stimulants
                

                
            

            

            

            
            

                推奨摂取タイミング： 30-45 minutes before meals or exercise
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Mild increase in heart rate (at high doses)
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                        
  • 
                            ⚠
                            GI discomfort
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            MAOIs
                        
    • 
                        
                        
  • 
                            ●
                            Other stimulants (avoid combination)
                        
    • 
                        
                        
  • 
                            ●
                            Caffeine (theoretical cardiovascular interaction)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： 100 mg/day; avoid combination with other stimulants
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Synephrine help with Fat Oxidation Enhancement?
            
        
        

            Based on 20 studies with 1,000 participants, there is moderate evidence from clinical studies that Synephrine may support Fat Oxidation Enhancement management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Synephrine should I take for Fat Oxidation Enhancement?
            
        
        

            Studies have used various dosages. A commonly studied range is 10-20 mg p-synephrine 1-3x/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Synephrine?
            
        
        

            Reported side effects may include Mild increase in heart rate (at high doses), Headache, GI discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Synephrine and Fat Oxidation Enhancement?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 20 peer-reviewed studies with 1,000 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
に関する他の成分： Fat Oxidation Enhancement

                    

                        
                        
                            Caffeine
                            A

                        
                        
                        
                            L-Carnitine
                            B

                        
                        
                        
                            Capsaicin
                            B

                        
                        
                    

                

                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。