ForskolinForskolin
thermogenic
别名: Coleus forskohlii, Coleonol, Colforsin
About
A diterpene compound from the root of Coleus forskohlii that directly activates adenylyl cyclase, increasing intracellular cAMP levels. Preliminary clinical trials suggest forskolin may support favorable changes in body composition, particularly in overweight men.
How It Works
Directly activates adenylyl cyclase, increasing intracellular cyclic AMP (cAMP) levels. Elevated cAMP activates protein kinase A and hormone-sensitive lipase, promoting lipolysis. Also stimulates thyroid hormone production and testosterone synthesis, which may support metabolic rate.
Evidence For Conditions
Side Effects
- Low blood pressure
- Increased heart rate
- Headache
- GI discomfort
Drug & Supplement Interactions
- Antihypertensives (additive blood pressure lowering)
- Blood thinners (theoretical)
- Nitrates
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Related Ingredients
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