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Garcinia Cambogia
Garcinia Cambogia

herbal

别名: Hydroxycitric Acid (HCA), Garcinia gummi-gutta, Malabar Tamarind, Brindleberry

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About





            

                
A tropical fruit extract containing hydroxycitric acid (HCA) that has been widely marketed for weight loss. However, Cochrane reviews and the landmark JAMA trial found evidence to be equivocal at best, and hepatotoxicity concerns have been reported in multi-ingredient products.

            

        

        

        
        
        

            

  
How It Works





            

                
Hydroxycitric acid (HCA) inhibits ATP-citrate lyase, the enzyme that converts citrate to acetyl-CoA for de novo fatty acid synthesis. Also increases hepatic glycogen synthesis, which may suppress appetite via glucoreceptor signaling in the brain. Serotonergic effects may further reduce appetite and emotional eating.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Obesity
                                    
                                
                                
                                    C

                                
                                
                                    12
                                
                                
                                    800
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Headache
                
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                    GI discomfort
                
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                    Liver toxicity (reported in multi-ingredient products)
                
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                    Nausea
                
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Drug & Supplement Interactions





            
    
                
                
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                    Diabetes medications (may affect blood sugar)
                
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                    Statins (potential liver concern)
                
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                    SSRIs (theoretical serotonergic interaction)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Green Coffee Bean Extract
                    
                
                
                
                    Bitter Orange Extract
                    
                
                
                
                    Hoodia
                    
                
                
                
                    Raspberry Ketones
                    
                
                
            

        

        
    


    
    












    

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