Ashwagandha ： Cortisol-Related Weight Gain

Q: Does Ashwagandha help with Cortisol-Related Weight Gain?

Based on 12 studies with 700 participants, there is moderate evidence from clinical studies that Ashwagandha may support Cortisol-Related Weight Gain management. Our evidence grade is B (Good Evidence).

Q: How much Ashwagandha should I take for Cortisol-Related Weight Gain?

Studies have used various dosages. A commonly studied range is 600 mg at bedtime. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Ashwagandha?

Reported side effects may include Drowsiness, GI discomfort, Rare liver injury at very high doses, Thyroid hormone changes. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Ashwagandha and Cortisol-Related Weight Gain?

We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 700 total participants. The overall direction of effect is positive.

B エビデンス少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。

Systematic review of 12 RCTs found significant cortisol reduction (27.9% in key study). An 8-week RCT (n=52) found reductions in body weight by 3.0% and BMI by 3.0% in chronically stressed adults. Ashwagandha addresses cortisol-driven visceral fat accumulation.

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結論

Key Study Findings

RCT n=90 12 weeks Double-blind

A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep …

Dose: 125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily vs: Placebo 効果: None < 0.05

Review

Can Ashwagandha Benefit the Endocrine System?-A Review.

Dose: None vs: Placebo 効果: None None

Key Statistics

研究数

700

参加者数

↑

Positive

グレード

Referenced Papers

A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled … RCT

Advances in therapy 2025

Can Ashwagandha Benefit the Endocrine System?-A Review. Review

International journal of … 2023 43 件の引用

GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Systematic Review

Phytotherapy research : … 2018 95 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

sleep:: 600 mg at bedtime
general:: 300-600 mg/day KSM-66 standardized extract
stresscortisol:: 600 mg/day

上限量： 1,200 mg/day; rare liver injury cases at very high or prolonged doses

研究で検討された用量

用量	期間	効果	N
125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily	12 weeks	Positive	90
None	--	Positive	--

推奨摂取タイミング： Morning for energy/cortisol; evening for sleep; with meals

Safety & Side Effects

報告されている副作用

⚠ Drowsiness
⚠ GI discomfort
⚠ Rare liver injury at very high doses
⚠ Thyroid hormone changes

既知の相互作用

● Thyroid medications (may increase thyroid hormone levels)
● Sedatives (additive drowsiness)
● Immunosuppressants (may stimulate immune system)
● Diabetes medications (may lower blood sugar)

耐容上限摂取量： 1,200 mg/day; rare liver injury cases at very high or prolonged doses

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does Ashwagandha help with Cortisol-Related Weight Gain?

Based on 12 studies with 700 participants, there is moderate evidence from clinical studies that Ashwagandha may support Cortisol-Related Weight Gain management. Our evidence grade is B (Good Evidence).

How much Ashwagandha should I take for Cortisol-Related Weight Gain?

Studies have used various dosages. A commonly studied range is 600 mg at bedtime. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Ashwagandha?

Reported side effects may include Drowsiness, GI discomfort, Rare liver injury at very high doses, Thyroid hormone changes. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Ashwagandha and Cortisol-Related Weight Gain?

We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 700 total participants. The overall direction of effect is positive.

に関する他の成分： Cortisol-Related Weight Gain

Omega-3 C

Ashwagandha 他の症状・状態について

Exercise Performance for Weight Loss B Emotional Eating C

総合評価

Systematic review of 12 RCTs found significant cortisol reduction (27.9% in key study). An 8-week RCT (n=52) found reductions in body weight by 3.0% and BMI by 3.0% in chronically …

Evidence Strength72%

High confidence

研究の内訳

RCT (1)Meta (0)Other (11)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る： Cortisol-Related Weight Gain

詳しく見る

References

[1] Manasvi Mahadevan et al.. Adv Ther. 2025. A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled … doi:10.1007/s12325-025-03327-z PubMed
[2] Michał Wiciński et al.. Int J Mol Sci. 2023. Can Ashwagandha Benefit the Endocrine System?-A Review. doi:10.3390/ijms242216513 PubMed
[3] Karen Savage et al.. Phytother Res. 2018. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. doi:10.1002/ptr.5940 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。