What is the recommended dosage for Ashwagandha?

Sleep: 600 mg at bedtime; General: 300-600 mg/day KSM-66 standardized extract; Stress Cortisol: 600 mg/day

What are the side effects of Ashwagandha?

Potential side effects include: Drowsiness, GI discomfort, Rare liver injury at very high doses, Thyroid hormone changes.

What is ashwagandha and how may it support weight management?

Ashwagandha (Withania somnifera) is an adaptogenic herb used in traditional Ayurvedic medicine. Some clinical studies suggest it may help reduce cortisol levels and stress-related eating behaviors. Research on its direct effects on body weight is limited but emerging.

What dosage of ashwagandha has been studied in clinical trials?

Clinical trials have used 300–600 mg per day of ashwagandha root extract standardized to withanolides, typically divided into two doses. Studies on stress and cortisol reduction typically lasted 8–12 weeks. KSM-66 and Sensoril are the most commonly studied branded extracts.

What are the potential side effects of ashwagandha?

Common side effects include mild drowsiness, gastrointestinal discomfort, and diarrhea. Ashwagandha may affect thyroid hormone levels and should be used cautiously by individuals with thyroid conditions. It is not recommended during pregnancy. Cases of liver injury have been reported rarely.

Ashwagandha
Ashwagandha

hormonal

別名: Withania somnifera, KSM-66, Sensoril, Indian Ginseng, Winter Cherry

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About

A withanolide-rich adaptogenic herb (Withania somnifera) with extensive clinical research supporting its role in modulating cortisol levels and the stress response. Systematic reviews demonstrate ashwagandha may support healthy body weight and composition in chronically stressed individuals.

How It Works

Withanolide-rich adaptogen that modulates the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol levels by 14-28% in clinical trials. Chronic cortisol elevation promotes visceral fat accumulation, insulin resistance, and stress-driven eating. Also improves thyroid function (T3/T4), testosterone levels, and sleep quality — all of which influence metabolic rate and body composition.

Evidence For Conditions

症状・状態	グレード	研究数	参加者数
Cortisol-Related Weight Gain	B	12	700	詳細を見る →
Exercise Performance for Weight Loss	B	8	500	詳細を見る →
Emotional Eating	C	5	300	詳細を見る →

Side Effects

Drowsiness
GI discomfort
Rare liver injury at very high doses
Thyroid hormone changes

Drug & Supplement Interactions

Thyroid medications (may increase thyroid hormone levels)
Sedatives (additive drowsiness)
Immunosuppressants (may stimulate immune system)
Diabetes medications (may lower blood sugar)

服用しているすべてのサプリメントについて、必ず医療提供者にお知らせください。摂取しているすべてのサプリメントについて、必ず医療専門家にお知らせください。

Related Ingredients

Maca DHEA Vitamin D

基本情報

用量: Sleep: 600 mg at bedtime; General: 300-600 mg/day KSM-66 standardized extract; Stress_Cortisol: 600 mg/day
剤形: capsule powder liquid extract gummy
天然の供給源: Withania somnifera root (Indian shrub, supplement form only)
上限量: 1,200 mg/day; rare liver injury cases at very high or prolonged doses
推奨摂取タイミング: Morning for energy/cortisol; evening for sleep; with meals

エビデンスの要約

Cortisol-Related Weight Gain B

Exercise Performance for Weight Loss B

Emotional Eating C

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。