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CLA için Obesity

B

Cochrane meta-analysis of 18 RCTs (n=807) found CLA at 3.2 g/day reduced body fat mass by 1.33 kg over 6-12 months without significant change in body weight, suggesting lean mass preservation. A 2-year RCT (n=134) found sustained fat reduction. Effects are modest and require long-term use.

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Sonuç

            
            
Cochrane meta-analysis of 18 RCTs (n=807) found CLA at 3.2 g/day reduced body fat mass by 1.33 kg over 6-12 months without significant change in body weight, suggesting lean mass preservation. A 2-year RCT (n=134) found sustained fat reduction. Effects are modest and require long-term use.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
18

        
Çalışmalar

    

    

        
807

        
Katılımcılar

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Derece

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Yaygın Kullanılan Dozajlar

                

                    
                    

                        
general:

                        
3.2-6.4 g/day mixed isomers

                    

                    
                    

                        
bodycomposition:

                        
3.4 g/day (50:50 c9,t11:t10,c12 blend)

                    

                    
                    

                        
minimumeffective:

                        
3.2 g/day for ≥12 weeks

                    

                    
                

                
                

                    Üst sınır: 6 g/day; higher doses may worsen insulin sensitivity
                

                
            

            

            

            
            

                En iyi alım zamanı: With meals; divide dose across 2-3 meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Bildirilen Yan Etkiler

                    
    
                        
                        
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                            ⚠
                            GI discomfort
                        
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                            May worsen insulin sensitivity at high doses
                        
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                            ⚠
                            Possible HDL reduction
                        
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                            ⚠
                            Fatty liver (in some rodent studies)
                        
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Bilinen Etkileşimler

                    
    
                        
                        
  • 
                            ●
                            Diabetes medications (may affect insulin sensitivity)
                        
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                            ●
                            Blood thinners (theoretical)
                        
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                        Tolere edilebilir üst alım: 6 g/day; higher doses may worsen insulin sensitivity
                    

                

                
            

            

                Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does CLA help with Obesity?
            
        
        

            Based on 18 studies with 807 participants, there is moderate evidence from clinical studies that CLA may support Obesity management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much CLA should I take for Obesity?
            
        
        

            Studies have used various dosages. A commonly studied range is 3.2-6.4 g/day mixed isomers. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of CLA?
            
        
        

            Reported side effects may include GI discomfort, May worsen insulin sensitivity at high doses, Possible HDL reduction, Fatty liver (in some rodent studies). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for CLA and Obesity?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 18 peer-reviewed studies with 807 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

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