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Iron ： Post-Bariatric Nutritional Support

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Iron deficiency occurs in 33-55% of post-bariatric patients. ASMBS guidelines recommend 45-60 mg elemental iron/day after gastric bypass. Ferrous bisglycinate is the preferred form for tolerability. Monitoring every 3-6 months is mandatory.

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            B

        

        

            
結論

            
            
Iron deficiency occurs in 33-55% of post-bariatric patients. ASMBS guidelines recommend 45-60 mg elemental iron/day after gastric bypass. Ferrous bisglycinate is the preferred form for tolerability. Monitoring every 3-6 months is mandatory.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                n=240
                
                
                520 weeks
                
                
                Open-label
                
            

            
                Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of …
            
            

                
                Dose: None
                
                
                vs: Laparoscopic Roux-en-Y gastric bypass (LRYGB)
                
                
                Outcome: Nutritional deficiency prevalence at 10 years
                
                
                効果: Iron deficiency: LSG 14% vs LRYGB 41%
                
                
                p=0.017 (iron deficiency)
                
            

            
            
対象集団: Severely obese adults undergoing bariatric surgery

            
        

        
        

            

                
                    Systematic Review
                
                
                
                
            

            
                Preoperative Micronutrient Repletion Strategies in Metabolic and Bariatric Surgery: A Systematic Review.
            
            

                
                Dose: Various (oral supplements, megadoses, injections)
                
                
                vs: Usual care or no treatment
                
                
                Outcome: Micronutrient status pre/post-surgery
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: Metabolic and bariatric surgery candidates

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Risks and limits of bariatric surgery: old solutions and a new potential option.
            
            

                
                Dose: None
                
                
                vs: Placebo
                
                
                
                効果: None
                
                
                None
                
            

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Copper deficiency anemia: review article.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Nutritional management of patients after bariatric surgery.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Nutritional management of patients after bariatric surgery.
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: None

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
10

        
研究数

    

    

        
1000

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Obesity surgery
                        2026
                        
                    

                

                
                

                    

                        
                            Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial.
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        The British journal …
                        2025
                        
                        10 件の引用
                        
                    

                

                
                

                    

                        
                            Preoperative Micronutrient Repletion Strategies in Metabolic and Bariatric Surgery: A Systematic Review.
                        
                        
                            
                                Systematic Review
                            
                            
                            
                        
                    

                    

                        Journal of the …
                        2025
                        
                        6 件の引用
                        
                    

                

                
                

                    

                        
                            Risks and limits of bariatric surgery: old solutions and a new potential option.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        European review for …
                        2023
                        
                        5 件の引用
                        
                    

                

                
                

                    

                        
                            The role of iron repletion in adult iron deficiency anemia and other diseases.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        European journal of …
                        2020
                        
                        137 件の引用
                        
                    

                

                
                

                    

                        
                            Copper deficiency anemia: review article.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Annals of hematology
                        2018
                        
                        234 件の引用
                        
                    

                

                
                

                    

                        
                            Nutritional management of patients after bariatric surgery.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        The American journal …
                        2006
                        
                        143 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
8-18 mg/day (RDA)

                    

                    
                    

                        
menstruatingwomen:

                        
18 mg/day

                    

                    
                    

                        
deficiencycorrection:

                        
100-200 mg elemental iron/day under medical guidance

                    

                    
                

                
                

                    上限量： 45 mg/day (elemental iron); excess iron increases oxidative stress
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                None
                                520 weeks
                                
                                    
                                    Positive
                                    
                                
                                240
                            

                            
                            

                                Various (oral supplements, megadoses, injections)
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： On empty stomach with vitamin C for absorption; avoid with calcium, coffee, tea
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Constipation
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea
                        
    • 
                        
                        
  • 
                            ⚠
                            Stomach pain
                        
    • 
                        
                        
  • 
                            ⚠
                            Black stools
                        
    • 
                        
                        
  • 
                            ⚠
                            Oxidative stress (excess iron)
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Levothyroxine (reduced absorption — take 4 hours apart)
                        
    • 
                        
                        
  • 
                            ●
                            Tetracycline antibiotics (reduced absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Calcium supplements (reduced absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Proton pump inhibitors (reduced absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： 45 mg/day (elemental iron); excess iron increases oxidative stress
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Iron help with Post-Bariatric Nutritional Support?
            
        
        

            Based on 10 studies with 1,000 participants, there is moderate evidence from clinical studies that Iron may support Post-Bariatric Nutritional Support management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Iron should I take for Post-Bariatric Nutritional Support?
            
        
        

            Studies have used various dosages. A commonly studied range is 8-18 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Iron?
            
        
        

            Reported side effects may include Constipation, Nausea, Stomach pain, Black stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Iron and Post-Bariatric Nutritional Support?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 1,000 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
に関する他の成分： Post-Bariatric Nutritional Support

                    

                        
                        
                            Vitamin B12
                            B

                        
                        
                        
                            Whey Protein
                            B

                        
                        
                    

                

                

                
                
                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Fatemeh Chinisaz et al..
      Obes Surg.
      2026.
      Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
      doi:10.1007/s11695-026-08597-2
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Ilmari Saarinen et al..
      Br J Surg.
      2025.
      Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial.
      doi:10.1093/bjs/znaf132
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Xueying Tang et al..
      J Acad Nutr Diet.
      2025.
      Preoperative Micronutrient Repletion Strategies in Metabolic and Bariatric Surgery: A Systematic Review.
      doi:10.1016/j.jand.2024.09.007
      PubMed
    
    4. 
    
    
  4. 
      [4]
      R Gambioli et al..
      Eur Rev Med Pharmacol Sci.
      2023.
      Risks and limits of bariatric surgery: old solutions and a new potential option.
      doi:10.26355/eurrev_202306_32822
      PubMed
    
    5. 
    
    
  5. 
      [5]
      Benjamin Elstrott et al..
      Eur J Haematol.
      2020.
      The role of iron repletion in adult iron deficiency anemia and other diseases.
      doi:10.1111/ejh.13345
      PubMed
    
    6. 
    
    
  6. 
      [6]
      Zin W Myint et al..
      Ann Hematol.
      2018.
      Copper deficiency anemia: review article.
      doi:10.1007/s00277-018-3407-5
      PubMed
    
    7. 
    
    
  7. 
      [7]
      Emmy Parkes.
      Am J Med Sci.
      2006.
      Nutritional management of patients after bariatric surgery.
      doi:10.1097/00000441-200604000-00007
      PubMed
    
    8. 
    
  















    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。