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Iron untuk Hypothyroid-Related Weight Gain

C

Iron is required for thyroid peroxidase (TPO), and iron deficiency impairs T4-to-T3 conversion and thyroid hormone synthesis. Meta-analysis of 22 RCTs found correction of iron deficiency improves exercise tolerance and VO2max. Supplement only when deficiency is confirmed.

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Kesimpulan

Iron is required for thyroid peroxidase (TPO), and iron deficiency impairs T4-to-T3 conversion and thyroid hormone synthesis. Meta-analysis of 22 RCTs found correction of iron deficiency improves exercise tolerance and VO2max. Supplement only when deficiency is confirmed.

Key Statistics

22

Studi

2000

Peserta

Positive

C

Peringkat

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
8-18 mg/day (RDA)
menstruatingwomen:
18 mg/day
deficiencycorrection:
100-200 mg elemental iron/day under medical guidance

Batas atas: 45 mg/day (elemental iron); excess iron increases oxidative stress

Waktu terbaik diminum: On empty stomach with vitamin C for absorption; avoid with calcium, coffee, tea

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Constipation
  • Nausea
  • Stomach pain
  • Black stools
  • Oxidative stress (excess iron)

Interaksi yang Diketahui

  • Levothyroxine (reduced absorption — take 4 hours apart)
  • Tetracycline antibiotics (reduced absorption)
  • Calcium supplements (reduced absorption)
  • Proton pump inhibitors (reduced absorption)

Asupan atas yang dapat ditoleransi: 45 mg/day (elemental iron); excess iron increases oxidative stress

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Iron help with Hypothyroid-Related Weight Gain?
Based on 22 studies with 2,000 participants, there is limited but promising evidence that Iron may support Hypothyroid-Related Weight Gain management. Our evidence grade is C (Some Evidence).
How much Iron should I take for Hypothyroid-Related Weight Gain?
Studies have used various dosages. A commonly studied range is 8-18 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Iron?
Reported side effects may include Constipation, Nausea, Stomach pain, Black stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Iron and Hypothyroid-Related Weight Gain?
We rate the evidence as Grade C (Some Evidence). This rating is based on 22 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Related Evidence

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